Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 2504264..2505084 Replicon chromosome
Accession NZ_CP107558
Organism Methylocystis sp. MJC1

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag OGR47_RS12230 Protein ID WP_165051735.1
Coordinates 2504572..2505084 (+) Length 171 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag OGR47_RS12225 Protein ID WP_165051733.1
Coordinates 2504264..2504584 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGR47_RS12210 (OGR47_12210) 2500049..2500636 + 588 WP_165051726.1 poly-gamma-glutamate hydrolase family protein -
OGR47_RS12215 (OGR47_12215) 2501007..2502410 - 1404 WP_165051728.1 ribosome biogenesis GTPase Der -
OGR47_RS12220 (OGR47_12220) 2502718..2504025 - 1308 WP_165051731.1 UDP-glucose/GDP-mannose dehydrogenase family protein -
OGR47_RS12225 (OGR47_12225) 2504264..2504584 + 321 WP_165051733.1 DUF1778 domain-containing protein Antitoxin
OGR47_RS12230 (OGR47_12230) 2504572..2505084 + 513 WP_165051735.1 GNAT family N-acetyltransferase Toxin
OGR47_RS12235 (OGR47_12235) 2505130..2505513 - 384 WP_165051737.1 DUF4180 domain-containing protein -
OGR47_RS12240 (OGR47_12240) 2505577..2506122 + 546 WP_246729683.1 AAA family ATPase -
OGR47_RS12245 (OGR47_12245) 2506397..2508847 + 2451 WP_253948116.1 spermidine synthase -
OGR47_RS12250 (OGR47_12250) 2508874..2509497 - 624 WP_165051742.1 putative 2OG-Fe(II) oxygenase -
OGR47_RS12255 (OGR47_12255) 2509625..2509918 - 294 Protein_2415 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(48-145)

Antitoxin

Vibrio phage ICP1, Orf50

(25-101)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 18331.10 Da        Isoelectric Point: 8.4938

>T261738 WP_165051735.1 NZ_CP107558:2504572-2505084 [Methylocystis sp. MJC1]
MGEVARAALSAPVPLTAEHDLSDFDCGEPVLNDWLRHRALRNESRFSRNYVVCAGKRVVAYYCVSAGAVERAAAPGKMRR
NAPDAIPVSVIGRLAASREHAGKGLGADLLSDALRRITAVSQSIGVAAVLVHAKDEAAKRFYLRCAEFIEYPADSGILFL
PIETVIRSLV

Download         Length: 513 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11682.27 Da        Isoelectric Point: 8.6582

>AT261738 WP_165051733.1 NZ_CP107558:2504264-2504584 [Methylocystis sp. MJC1]
MSRSSSSDSLEAAARPSTADAKASINLRIEANTRQLIDEAAAVLGKTRTEFMIESARRQAIDVLLDQRLFALDPDRYDAF
MRALDNPPAPGPKLESLLRRVPAWGK

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References