Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1317607..1318112 Replicon chromosome
Accession NZ_CP107558
Organism Methylocystis sp. MJC1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OGR47_RS06310 Protein ID WP_165047958.1
Coordinates 1317858..1318112 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag OGR47_RS06305 Protein ID WP_165047956.1
Coordinates 1317607..1317861 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGR47_RS06285 (OGR47_06285) 1313414..1313686 + 273 WP_165047947.1 hypothetical protein -
OGR47_RS06290 (OGR47_06290) 1313867..1314514 + 648 WP_165047949.1 hypothetical protein -
OGR47_RS06295 (OGR47_06295) 1314622..1315431 - 810 WP_165047951.1 hypothetical protein -
OGR47_RS06300 (OGR47_06300) 1315740..1317548 + 1809 WP_165047953.1 translation elongation factor 4 -
OGR47_RS06305 (OGR47_06305) 1317607..1317861 + 255 WP_165047956.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OGR47_RS06310 (OGR47_06310) 1317858..1318112 + 255 WP_165047958.1 Txe/YoeB family addiction module toxin Toxin
OGR47_RS06315 (OGR47_06315) 1318201..1318563 + 363 WP_165047960.1 endonuclease domain-containing protein -
OGR47_RS06320 (OGR47_06320) 1318612..1319514 - 903 WP_165047962.1 EamA family transporter -
OGR47_RS06325 (OGR47_06325) 1319641..1320375 - 735 WP_165047964.1 class I SAM-dependent methyltransferase -
OGR47_RS06330 (OGR47_06330) 1320429..1321129 - 701 Protein_1248 MOSC domain-containing protein -
OGR47_RS06335 (OGR47_06335) 1321252..1321584 + 333 WP_165047967.1 hypothetical protein -
OGR47_RS06340 (OGR47_06340) 1321673..1321933 + 261 WP_165047969.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10063.52 Da        Isoelectric Point: 8.5012

>T261737 WP_165047958.1 NZ_CP107558:1317858-1318112 [Methylocystis sp. MJC1]
MKLVFSESAWEDYLHWQAQDAKILDRINSLIKECQRTPFTGTGKPEPLRGDLRGWWSRRITLEHRLVYRVEGESLLIAQC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9335.52 Da        Isoelectric Point: 5.1767

>AT261737 WP_165047956.1 NZ_CP107558:1317607-1317861 [Methylocystis sp. MJC1]
MRTTSYSDLRKNLAATLDRVTEDHEPVVITRDRGKPAAVLISLEDFASYEETAYLLKSPRNAERLLASIKELEAGGGAER
KLSE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References