Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1317607..1318112 Replicon chromosome
Accession NZ_CP107558
Organism Methylocystis sp. MJC1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OGR47_RS06310 Protein ID WP_165047958.1
Coordinates 1317858..1318112 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag OGR47_RS06305 Protein ID WP_165047956.1
Coordinates 1317607..1317861 (+) Length 85 a.a.

Genomic Context

OGR47_RS06285OGR47_RS06290OGR47_RS06300OGR47_RS06305OGR47_RS06310OGR47_RS06315OGR47_RS06335OGR47_RS06340OGR47_RS06295OGR47_RS06320OGR47_RS06325OGR47_RS06330
Location: 1313414..1313686 (273 bp)
Type: Others
Protein ID: WP_165047947.1
Location: 1313867..1314514 (648 bp)
Type: Others
Protein ID: WP_165047949.1
Location: 1315740..1317548 (1809 bp)
Type: Others
Protein ID: WP_165047953.1
Location: 1317607..1317861 (255 bp)
Type: Antitoxin
Protein ID: WP_165047956.1
Location: 1317858..1318112 (255 bp)
Type: Toxin
Protein ID: WP_165047958.1
Location: 1318201..1318563 (363 bp)
Type: Others
Protein ID: WP_165047960.1
Location: 1321252..1321584 (333 bp)
Type: Others
Protein ID: WP_165047967.1
Location: 1321673..1321933 (261 bp)
Type: Others
Protein ID: WP_165047969.1
Location: 1314622..1315431 (810 bp)
Type: Others
Protein ID: WP_165047951.1
Location: 1318612..1319514 (903 bp)
Type: Others
Protein ID: WP_165047962.1
Location: 1319641..1320375 (735 bp)
Type: Others
Protein ID: WP_165047964.1
Location: 1320429..1321129 (701 bp)
Type: Others
Protein ID: Protein_1248
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OGR47_RS06285 (OGR47_06285)1313414..1313686+273WP_165047947.1hypothetical protein-
OGR47_RS06290 (OGR47_06290)1313867..1314514+648WP_165047949.1hypothetical protein-
OGR47_RS06295 (OGR47_06295)1314622..1315431-810WP_165047951.1hypothetical protein-
OGR47_RS06300 (OGR47_06300)1315740..1317548+1809WP_165047953.1translation elongation factor 4-
OGR47_RS06305 (OGR47_06305)1317607..1317861+255WP_165047956.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
OGR47_RS06310 (OGR47_06310)1317858..1318112+255WP_165047958.1Txe/YoeB family addiction module toxinToxin
OGR47_RS06315 (OGR47_06315)1318201..1318563+363WP_165047960.1endonuclease domain-containing protein-
OGR47_RS06320 (OGR47_06320)1318612..1319514-903WP_165047962.1EamA family transporter-
OGR47_RS06325 (OGR47_06325)1319641..1320375-735WP_165047964.1class I SAM-dependent methyltransferase-
OGR47_RS06330 (OGR47_06330)1320429..1321129-701Protein_1248MOSC domain-containing protein-
OGR47_RS06335 (OGR47_06335)1321252..1321584+333WP_165047967.1hypothetical protein-
OGR47_RS06340 (OGR47_06340)1321673..1321933+261WP_165047969.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10063.52 Da        Isoelectric Point: 8.5012

>T261737 WP_165047958.1 NZ_CP107558:1317858-1318112 [Methylocystis sp. MJC1]
MKLVFSESAWEDYLHWQAQDAKILDRINSLIKECQRTPFTGTGKPEPLRGDLRGWWSRRITLEHRLVYRVEGESLLIAQC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9335.52 Da        Isoelectric Point: 5.1767

>AT261737 WP_165047956.1 NZ_CP107558:1317607-1317861 [Methylocystis sp. MJC1]
MRTTSYSDLRKNLAATLDRVTEDHEPVVITRDRGKPAAVLISLEDFASYEETAYLLKSPRNAERLLASIKELEAGGGAER
KLSE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References