261736

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 3544644..3545561 Replicon chromosome
Accession NZ_CP107557
Organism Bacillus velezensis strain CPA1-1

Toxin (Protein)


Gene name spoIISA Uniprot ID I2HQ15
Locus tag OGL87_RS17375 Protein ID WP_007407256.1
Coordinates 3544644..3545390 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag OGL87_RS17380 Protein ID WP_003154807.1
Coordinates 3545391..3545561 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGL87_RS17355 (OGL87_17355) 3540037..3540987 - 951 WP_032874618.1 ring-cleaving dioxygenase -
OGL87_RS17360 (OGL87_17360) 3541309..3542625 + 1317 WP_032874616.1 amino acid permease -
OGL87_RS17365 (OGL87_17365) 3542911..3543528 + 618 WP_032874614.1 DUF47 domain-containing protein -
OGL87_RS17370 (OGL87_17370) 3543541..3544539 + 999 WP_032874611.1 inorganic phosphate transporter -
OGL87_RS17375 (OGL87_17375) 3544644..3545390 + 747 WP_007407256.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
OGL87_RS17380 (OGL87_17380) 3545391..3545561 + 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
OGL87_RS17385 (OGL87_17385) 3545658..3545783 + 126 WP_003154809.1 hypothetical protein -
OGL87_RS17390 (OGL87_17390) 3545818..3546696 - 879 WP_032874609.1 N-acetylmuramoyl-L-alanine amidase -
OGL87_RS17395 (OGL87_17395) 3546710..3546973 - 264 WP_003154813.1 phage holin -
OGL87_RS17400 (OGL87_17400) 3546987..3547250 - 264 WP_003154815.1 hemolysin XhlA family protein -
OGL87_RS17405 (OGL87_17405) 3547302..3548063 - 762 WP_032874607.1 hypothetical protein -
OGL87_RS17410 (OGL87_17410) 3548120..3548317 - 198 WP_032874605.1 XkdX family protein -
OGL87_RS17415 (OGL87_17415) 3548322..3548693 - 372 WP_032874603.1 XkdW family protein -
OGL87_RS17420 (OGL87_17420) 3548706..3550328 - 1623 WP_032874601.1 pyocin knob domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29077.57 Da        Isoelectric Point: 4.7755

>T261736 WP_007407256.1 NZ_CP107557:3544644-3545390 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT261736 WP_003154807.1 NZ_CP107557:3545391-3545561 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB I2HQ15

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References