261734

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1218117..1219034 Replicon chromosome
Accession NZ_CP107556
Organism Bacillus velezensis strain Bacillus velezensis F3A

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag OF857_RS06475 Protein ID WP_057079950.1
Coordinates 1218288..1219034 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag OF857_RS06470 Protein ID WP_003154807.1
Coordinates 1218117..1218287 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OF857_RS06430 (OF857_06430) 1213350..1214972 + 1623 WP_166706517.1 pyocin knob domain-containing protein -
OF857_RS06435 (OF857_06435) 1214985..1215356 + 372 WP_070081681.1 XkdW family protein -
OF857_RS06440 (OF857_06440) 1215361..1215558 + 198 WP_168237133.1 XkdX family protein -
OF857_RS06445 (OF857_06445) 1215615..1216376 + 762 WP_070081683.1 phage portal protein -
OF857_RS06450 (OF857_06450) 1216428..1216691 + 264 WP_003154815.1 hemolysin XhlA family protein -
OF857_RS06455 (OF857_06455) 1216705..1216968 + 264 WP_003154813.1 phage holin -
OF857_RS06460 (OF857_06460) 1216982..1217860 + 879 WP_264101516.1 N-acetylmuramoyl-L-alanine amidase -
OF857_RS06465 (OF857_06465) 1217895..1218020 - 126 WP_003154809.1 hypothetical protein -
OF857_RS06470 (OF857_06470) 1218117..1218287 - 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
OF857_RS06475 (OF857_06475) 1218288..1219034 - 747 WP_057079950.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
OF857_RS06480 (OF857_06480) 1219139..1220137 - 999 WP_003154805.1 inorganic phosphate transporter -
OF857_RS06485 (OF857_06485) 1220150..1220767 - 618 WP_003154804.1 DUF47 domain-containing protein -
OF857_RS06490 (OF857_06490) 1221054..1222370 - 1317 WP_003154801.1 amino acid permease -
OF857_RS06495 (OF857_06495) 1222693..1223643 + 951 WP_039251754.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29033.52 Da        Isoelectric Point: 4.7755

>T261734 WP_057079950.1 NZ_CP107556:c1219034-1218288 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVVGAMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYGEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT261734 WP_003154807.1 NZ_CP107556:c1218287-1218117 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References