Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2744471..2745078 Replicon chromosome
Accession NZ_CP107548
Organism Pusillimonas sp. M17

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OEG81_RS12925 Protein ID WP_264129663.1
Coordinates 2744782..2745078 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OEG81_RS12920 Protein ID WP_264129662.1
Coordinates 2744471..2744776 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEG81_RS12900 (OEG81_12900) 2740368..2741339 - 972 WP_264129659.1 tripartite tricarboxylate transporter substrate binding protein -
OEG81_RS12905 (OEG81_12905) 2741378..2742106 - 729 WP_264129660.1 GntR family transcriptional regulator -
OEG81_RS12910 (OEG81_12910) 2742192..2743529 - 1338 WP_264129661.1 chloride channel protein -
OEG81_RS12915 (OEG81_12915) 2743812..2744447 + 636 WP_264132595.1 peptidoglycan DD-metalloendopeptidase family protein -
OEG81_RS12920 (OEG81_12920) 2744471..2744776 - 306 WP_264129662.1 putative addiction module antidote protein Antitoxin
OEG81_RS12925 (OEG81_12925) 2744782..2745078 - 297 WP_264129663.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OEG81_RS12930 (OEG81_12930) 2745265..2746521 - 1257 WP_264129664.1 NADP-dependent isocitrate dehydrogenase -
OEG81_RS12935 (OEG81_12935) 2746714..2747142 + 429 WP_264129665.1 DUF1841 family protein -
OEG81_RS12940 (OEG81_12940) 2747244..2747606 - 363 WP_264129666.1 cytochrome c -
OEG81_RS12945 (OEG81_12945) 2747619..2747972 - 354 WP_264129667.1 c-type cytochrome -
OEG81_RS12950 (OEG81_12950) 2748128..2749000 + 873 WP_264129668.1 MoxR family ATPase -
OEG81_RS12955 (OEG81_12955) 2749050..2749664 + 615 WP_264129669.1 GNAT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Uncharacterized protein HI1420

(12-98)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10947.68 Da        Isoelectric Point: 10.0424

>T261728 WP_264129663.1 NZ_CP107548:c2745078-2744782 [Pusillimonas sp. M17]
MFTVKQTPEFERWIGGLKDGMARIRLAKRLDKVQRGNLGDVAPIGEGVSEMREHFGPGWRMYYVQRGDVLIVMLGGGDKS
TQNADIKQAIALAKTLQE

Download         Length: 297 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10962.53 Da        Isoelectric Point: 6.2231

>AT261728 WP_264129662.1 NZ_CP107548:c2744776-2744471 [Pusillimonas sp. M17]
MTKTSKISELPEFDMAEVLKTDEDIANYLTVVLEENDPAELSHALGVIARARGMTEVARASGLTREALYKALRPGSHPRF
DTIARVCAALGVQLTARPAHS

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References