Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1709440..1710110 Replicon chromosome
Accession NZ_CP107548
Organism Pusillimonas sp. M17

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OEG81_RS08135 Protein ID WP_264132220.1
Coordinates 1709685..1710110 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OEG81_RS08130 Protein ID WP_264132219.1
Coordinates 1709440..1709688 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEG81_RS08105 (OEG81_08105) 1704736..1705209 - 474 WP_264132215.1 GNAT family N-acetyltransferase -
OEG81_RS08110 (OEG81_08110) 1705269..1706057 - 789 WP_264132216.1 alpha/beta fold hydrolase -
OEG81_RS08115 (OEG81_08115) 1706100..1707284 - 1185 WP_264132217.1 YbfB/YjiJ family MFS transporter -
OEG81_RS08120 (OEG81_08120) 1707394..1708980 + 1587 WP_264132218.1 glutamine-hydrolyzing GMP synthase -
OEG81_RS08125 (OEG81_08125) 1709059..1709145 + 87 Protein_1596 conjugal transfer protein TraJ -
OEG81_RS08130 (OEG81_08130) 1709440..1709688 + 249 WP_264132219.1 Arc family DNA-binding protein Antitoxin
OEG81_RS08135 (OEG81_08135) 1709685..1710110 + 426 WP_264132220.1 type II toxin-antitoxin system VapC family toxin Toxin
OEG81_RS08140 (OEG81_08140) 1710237..1711754 - 1518 WP_264132221.1 FAD-dependent oxidoreductase -
OEG81_RS08145 (OEG81_08145) 1711799..1712302 + 504 WP_264132222.1 MarR family winged helix-turn-helix transcriptional regulator -
OEG81_RS08150 (OEG81_08150) 1712413..1713180 + 768 WP_264132223.1 DUF72 domain-containing protein -
OEG81_RS08155 (OEG81_08155) 1713262..1714068 - 807 WP_264132224.1 DUF72 domain-containing protein -
OEG81_RS08160 (OEG81_08160) 1714296..1715033 + 738 WP_264132535.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15248.56 Da        Isoelectric Point: 4.4237

>T261727 WP_264132220.1 NZ_CP107548:1709685-1710110 [Pusillimonas sp. M17]
MILLDTNVISEQFRAVPDESVIDWLNRQPLETLYLASMTVAELRACVALMPAGKRRTVLSDNIEHQVLPVFVGRVLSFDM
ACTRAYADVLAAARKSGSGIEAADAIIAAIALDNGFSVATRDVSPFLAAGVKVISPWEDQE

Download         Length: 426 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9126.51 Da        Isoelectric Point: 8.0567

>AT261727 WP_264132219.1 NZ_CP107548:1709440-1709688 [Pusillimonas sp. M17]
MRAVTIRNVPEEVHRAIRVRAAQNGRTLQAEMCEILATAVKPEGRVKLGDLLADIGRKVKLTDEEMAVFDRDHSPARAAS
FE

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References