Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1205754..1206359 Replicon chromosome
Accession NZ_CP107548
Organism Pusillimonas sp. M17

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OEG81_RS05800 Protein ID WP_264131758.1
Coordinates 1206069..1206359 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag OEG81_RS05795 Protein ID WP_264131757.1
Coordinates 1205754..1206056 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEG81_RS05770 (OEG81_05770) 1201087..1202247 + 1161 WP_264131752.1 ABC transporter substrate-binding protein -
OEG81_RS05775 (OEG81_05775) 1202291..1203160 - 870 WP_264131753.1 hypothetical protein -
OEG81_RS05780 (OEG81_05780) 1203290..1204420 + 1131 WP_264131754.1 cupin domain-containing protein -
OEG81_RS05785 (OEG81_05785) 1204515..1205465 + 951 WP_264131755.1 LysR family transcriptional regulator -
OEG81_RS05790 (OEG81_05790) 1205438..1205683 - 246 WP_264131756.1 hypothetical protein -
OEG81_RS05795 (OEG81_05795) 1205754..1206056 - 303 WP_264131757.1 putative addiction module antidote protein Antitoxin
OEG81_RS05800 (OEG81_05800) 1206069..1206359 - 291 WP_264131758.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OEG81_RS05805 (OEG81_05805) 1206523..1206813 + 291 Protein_1140 transposase -
OEG81_RS05810 (OEG81_05810) 1207320..1208012 + 693 WP_264131759.1 HAD family phosphatase -
OEG81_RS05815 (OEG81_05815) 1208110..1208922 - 813 WP_264131760.1 arylamine N-acetyltransferase -
OEG81_RS05820 (OEG81_05820) 1209249..1210910 + 1662 WP_264131761.1 CTP synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1206523..1206867 344


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(48-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10961.51 Da        Isoelectric Point: 8.0307

>T261724 WP_264131758.1 NZ_CP107548:c1206359-1206069 [Pusillimonas sp. M17]
MKTIHTTDTFDDWFVGLRDRMAQKRIQARIRRAEFGNFGDCEPVGEGVSEMRIHYGPGYRVYFVQRGLEIVILLAGGDKS
TQSQDIKTALNLVQQL

Download         Length: 291 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10797.51 Da        Isoelectric Point: 5.6079

>AT261724 WP_264131757.1 NZ_CP107548:c1206056-1205754 [Pusillimonas sp. M17]
MGTIKLRKWDIIEYLKTEEDMVMYLQACMDEAGDDAAFIAAALGDIARAKGMTQLAKDTGLGRESLYKALSGEGNPSFGT
ILKVMHALGIKLHPEAATHA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References