Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 981282..981873 Replicon chromosome
Accession NZ_CP107548
Organism Pusillimonas sp. M17

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OEG81_RS04710 Protein ID WP_264131566.1
Coordinates 981577..981873 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag OEG81_RS04705 Protein ID WP_264131565.1
Coordinates 981282..981575 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEG81_RS04680 (OEG81_04680) 976416..977372 + 957 WP_264131561.1 LysR family transcriptional regulator -
OEG81_RS04685 (OEG81_04685) 977422..978717 - 1296 WP_264131562.1 phospholipase A -
OEG81_RS04695 (OEG81_04695) 979026..980696 + 1671 WP_264131563.1 ATP-binding cassette domain-containing protein -
OEG81_RS04700 (OEG81_04700) 980856..981155 + 300 WP_264131564.1 putative quinol monooxygenase -
OEG81_RS04705 (OEG81_04705) 981282..981575 - 294 WP_264131565.1 putative addiction module antidote protein Antitoxin
OEG81_RS04710 (OEG81_04710) 981577..981873 - 297 WP_264131566.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OEG81_RS04715 (OEG81_04715) 982052..982642 - 591 WP_264131567.1 TetR/AcrR family transcriptional regulator -
OEG81_RS04720 (OEG81_04720) 982719..983432 + 714 WP_264131568.1 SDR family oxidoreductase -
OEG81_RS04725 (OEG81_04725) 983524..984141 - 618 WP_264131569.1 nucleotidyltransferase family protein -
OEG81_RS04730 (OEG81_04730) 984278..985177 - 900 WP_264131570.1 LysR family transcriptional regulator -
OEG81_RS04735 (OEG81_04735) 985279..986478 + 1200 WP_264131571.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(4-91)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11146.94 Da        Isoelectric Point: 10.1887

>T261723 WP_264131566.1 NZ_CP107548:c981873-981577 [Pusillimonas sp. M17]
MIELKQTKTYEKWEARLRDKRAKTIIAARLMRLAEGLPGDIESVGEGVNELRIHYGPGYRVYFQRRGNLLVVLLCGGDKS
TQARDIAAAKKLAKEWSE

Download         Length: 297 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10475.02 Da        Isoelectric Point: 5.8373

>AT261723 WP_264131565.1 NZ_CP107548:c981575-981282 [Pusillimonas sp. M17]
MTEKLTTYDPATALVDDEEIAFFMADAFETGDAAYIAKALGVVARAKGMTEIAKKTGLSREQLYRSFSERGNPTLKTTLA
VMRALGVDMTAKPHVAS

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References