Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-MazE
Location 232245..232905 Replicon chromosome
Accession NZ_CP107548
Organism Pusillimonas sp. M17

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag OEG81_RS01085 Protein ID WP_264130846.1
Coordinates 232630..232905 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag OEG81_RS01080 Protein ID WP_264130845.1
Coordinates 232245..232505 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEG81_RS01050 (OEG81_01050) 227579..228112 - 534 WP_264130839.1 3-isopropylmalate dehydratase -
OEG81_RS01055 (OEG81_01055) 228109..229380 - 1272 WP_264130840.1 3-isopropylmalate dehydratase large subunit -
OEG81_RS01060 (OEG81_01060) 229600..230028 + 429 WP_264130841.1 hypothetical protein -
OEG81_RS01065 (OEG81_01065) 230025..230417 + 393 WP_264130842.1 hypothetical protein -
OEG81_RS01070 (OEG81_01070) 230434..230904 + 471 WP_264130843.1 hypothetical protein -
OEG81_RS01075 (OEG81_01075) 230942..232063 - 1122 WP_264130844.1 hypothetical protein -
OEG81_RS01080 (OEG81_01080) 232245..232505 + 261 WP_264130845.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
OEG81_RS01085 (OEG81_01085) 232630..232905 + 276 WP_264130846.1 PIN domain-containing protein Toxin
OEG81_RS01090 (OEG81_01090) 233168..233566 + 399 WP_264130848.1 transposase -
OEG81_RS01095 (OEG81_01095) 233563..233907 + 345 WP_264130849.1 IS66 family insertion sequence element accessory protein TnpB -
OEG81_RS01100 (OEG81_01100) 233999..235591 + 1593 WP_264130850.1 IS66 family transposase -
OEG81_RS01105 (OEG81_01105) 235593..235955 - 363 WP_264130851.1 hypothetical protein -
OEG81_RS01110 (OEG81_01110) 235993..236562 - 570 WP_264130852.1 YdcF family protein -
OEG81_RS01115 (OEG81_01115) 236561..236797 + 237 WP_264130853.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 233563..233907 344


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 9918.24 Da        Isoelectric Point: 5.4943

>T261722 WP_264130846.1 NZ_CP107548:232630-232905 [Pusillimonas sp. M17]
MHYGLEKRPEATRLHAAAAEFLMRVDTLAWDNAVAETYGQMRNQLERNGRVLGSLDMLIAAHALHTGSVLVTNDQAFAAI
PGLGIEDWTGA

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 10253.56 Da        Isoelectric Point: 10.6822

>AT261722 WP_264130845.1 NZ_CP107548:232245-232505 [Pusillimonas sp. M17]
MSHVAKLFINGRRRAVRLPAAYRFDTKEVFIRKDPETGDAILSRRPETWDSFFRTIKDKVGQDSFLGNTERDQKQGHRDP
FKEWRE

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References