261721

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/HTH(antitoxin)
Location 4202216..4202685 Replicon chromosome
Accession NZ_CP107532
Organism Methylobacterium sp. FF17

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag OF380_RS19980 Protein ID WP_264047021.1
Coordinates 4202216..4202464 (-) Length 83 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag OF380_RS19985 Protein ID WP_264047022.1
Coordinates 4202461..4202685 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OF380_RS19955 4197372..4198355 + 984 WP_264047013.1 SMP-30/gluconolactonase/LRE family protein -
OF380_RS19960 4198390..4199571 + 1182 WP_264047015.1 major royal jelly family protein -
OF380_RS19965 4199679..4200836 + 1158 WP_264047017.1 OpgC domain-containing protein -
OF380_RS19970 4200849..4201517 - 669 WP_264047019.1 heme exporter protein CcmB -
OF380_RS19975 4201514..4202167 - 654 WP_264047020.1 heme ABC exporter ATP-binding protein CcmA -
OF380_RS19980 4202216..4202464 - 249 WP_264047021.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OF380_RS19985 4202461..4202685 - 225 WP_264047022.1 CopG family transcriptional regulator Antitoxin
OF380_RS19990 4202987..4205686 + 2700 WP_264047023.1 aconitate hydratase AcnA -
OF380_RS19995 4205904..4207211 + 1308 WP_264047025.1 dihydroorotase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(26-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9301.71 Da        Isoelectric Point: 12.2592

>T261721 WP_264047021.1 NZ_CP107532:c4202464-4202216 [Methylobacterium sp. FF17]
MSSQVPRNANSPGSTKRRPGASWSFLRDRVSPLDDPRAIGEALKGSRLGNFRKFRIGDFRVIADNALRILVIRIVHRRDV
YP

Download         Length: 249 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 7901.96 Da        Isoelectric Point: 5.0347

>AT261721 WP_264047022.1 NZ_CP107532:c4202685-4202461 [Methylobacterium sp. FF17]
MLALRLPPEIEDGLGALARRTGRSKDDHACGAILRHLENLENLAAVEQRLAAVQGGESDPVPVKDLLSRYGAAD

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References