Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4755067..4755212 Replicon chromosome
Accession NZ_CP107518
Organism Klebsiella pneumoniae strain CRKP_1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4755103..4755205 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4755067..4755212 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH528_RS23320 4750197..4752257 + 2061 WP_004151449.1 oligopeptidase B -
OH528_RS23325 4752261..4752920 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH528_RS23330 4752999..4753229 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH528_RS23335 4753342..4753716 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH528_RS23340 4753720..4754589 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH528_RS23345 4754606..4754944 + 339 WP_002911404.1 YebY family protein -
- 4755067..4755212 - 146 - - Antitoxin
- 4755103..4755205 + 103 - - Toxin
OH528_RS23350 4755580..4755723 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH528_RS23355 4755828..4756796 - 969 WP_004151446.1 VirK/YbjX family protein -
OH528_RS23360 4756953..4757606 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH528_RS23365 4757603..4757794 - 192 WP_002911395.1 YebW family protein -
OH528_RS23370 4757892..4758131 - 240 WP_002911393.1 YebV family protein -
OH528_RS23375 4758247..4759680 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T261696 NZ_CP107518:4755103-4755205 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT261696 NZ_CP107518:c4755212-4755067 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References