Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2022241..2022386 | Replicon | chromosome |
| Accession | NZ_CP107503 | ||
| Organism | Klebsiella pneumoniae strain CRKP_4 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2022277..2022379 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2022241..2022386 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OH526_RS09905 | 2017371..2019431 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| OH526_RS09910 | 2019435..2020094 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| OH526_RS09915 | 2020173..2020403 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| OH526_RS09920 | 2020516..2020890 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| OH526_RS09925 | 2020894..2021763 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| OH526_RS09930 | 2021780..2022118 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2022241..2022386 | - | 146 | - | - | Antitoxin |
| - | 2022277..2022379 | + | 103 | - | - | Toxin |
| OH526_RS09935 | 2022754..2022897 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| OH526_RS09940 | 2023002..2023970 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| OH526_RS09945 | 2024127..2024780 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| OH526_RS09950 | 2024777..2024968 | - | 192 | WP_002911395.1 | YebW family protein | - |
| OH526_RS09955 | 2025066..2025305 | - | 240 | WP_002911393.1 | YebV family protein | - |
| OH526_RS09960 | 2025421..2026854 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T261614 NZ_CP107503:2022277-2022379 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT261614 NZ_CP107503:c2022386-2022241 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
