Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4755065..4755210 Replicon chromosome
Accession NZ_CP107488
Organism Klebsiella pneumoniae strain CRKP_7

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4755101..4755203 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4755065..4755210 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH500_RS23315 4750195..4752255 + 2061 WP_004151449.1 oligopeptidase B -
OH500_RS23320 4752259..4752918 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH500_RS23325 4752997..4753227 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH500_RS23330 4753340..4753714 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH500_RS23335 4753718..4754587 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH500_RS23340 4754604..4754942 + 339 WP_002911404.1 YebY family protein -
- 4755065..4755210 - 146 - - Antitoxin
- 4755101..4755203 + 103 - - Toxin
OH500_RS23345 4755578..4755721 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH500_RS23350 4755826..4756794 - 969 WP_004151446.1 VirK/YbjX family protein -
OH500_RS23355 4756951..4757604 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH500_RS23360 4757601..4757792 - 192 WP_002911395.1 YebW family protein -
OH500_RS23365 4757890..4758129 - 240 WP_002911393.1 YebV family protein -
OH500_RS23370 4758245..4759678 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T261543 NZ_CP107488:4755101-4755203 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT261543 NZ_CP107488:c4755210-4755065 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References