Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-PHD
Location 614117..614781 Replicon chromosome
Accession NC_016943
Organism Blastococcus saxobsidens DD2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BLASA_RS02875 Protein ID WP_014374504.1
Coordinates 614117..614521 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BLASA_RS02880 Protein ID WP_041775573.1
Coordinates 614518..614781 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLASA_RS02850 609840..610835 - 996 WP_014374498.1 Gfo/Idh/MocA family oxidoreductase -
BLASA_RS02855 610874..611149 + 276 WP_014374499.1 DUF4031 domain-containing protein -
BLASA_RS02860 611091..611747 - 657 WP_014374500.1 metal-dependent phosphohydrolase -
BLASA_RS02865 611744..613009 - 1266 WP_014374501.1 ArgE/DapE family deacylase -
BLASA_RS02870 613072..613782 + 711 WP_014374502.1 DUF2510 domain-containing protein -
BLASA_RS02875 614117..614521 - 405 WP_014374504.1 type II toxin-antitoxin system VapC family toxin Toxin
BLASA_RS02880 614518..614781 - 264 WP_041775573.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BLASA_RS02885 614798..616582 - 1785 WP_014374506.1 DEAD/DEAH box helicase family protein -
BLASA_RS24785 617123..617260 + 138 WP_014374507.1 hypothetical protein -
BLASA_RS02895 617328..619013 - 1686 WP_014374508.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(30-126)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(7-44)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14288.36 Da        Isoelectric Point: 4.5184

>T26133 WP_014374504.1 NC_016943:c614521-614117 [Blastococcus saxobsidens DD2]
MTIDADRAALGLADTSLFSAVEQQRPLSGHPPERIAVSVVTIAELRLGVLAAPDGATRARRLETLTLADDLEPLPIDRSV
AAAWAGLRLTLRDTGRRMPLNDSWIAATALALDLPVVTQDADYDGVPGLQVIRV

Download         Length: 405 bp

>T26133 NC_016943:c614521-614117 [Blastococcus saxobsidens DD2]
ATGACGATCGATGCGGACCGAGCGGCTCTCGGTCTCGCGGACACGTCTCTGTTCAGCGCCGTCGAGCAGCAACGCCCGCT
GTCCGGACATCCGCCTGAGCGGATCGCTGTCTCGGTCGTCACGATCGCGGAGCTACGGCTCGGCGTGCTTGCGGCCCCTG
ATGGCGCGACCCGCGCCCGGCGGCTCGAGACGCTGACACTCGCGGACGACCTGGAGCCGTTGCCGATCGACCGGTCCGTC
GCAGCCGCTTGGGCCGGCCTGCGCCTGACTCTGCGCGACACCGGCCGGCGGATGCCGCTCAACGATTCGTGGATCGCCGC
CACGGCACTCGCGCTGGACCTACCCGTCGTCACGCAGGACGCCGACTACGACGGCGTGCCGGGTCTCCAGGTCATCCGCG
TCTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9393.71 Da        Isoelectric Point: 5.6380

>AT26133 WP_041775573.1 NC_016943:c614781-614518 [Blastococcus saxobsidens DD2]
MLVSTDVPARELRNDVSGVLRRVQAGERLRVTVSGRPVAELVPLPSRQPSMAWDHFVRHISGGLADAALADDLAALLPDT
TDDVPVR

Download         Length: 264 bp

>AT26133 NC_016943:c614781-614518 [Blastococcus saxobsidens DD2]
ATGCTCGTGAGTACGGACGTTCCCGCTCGCGAGCTTCGTAACGACGTCAGCGGCGTGCTGCGCCGGGTCCAGGCAGGAGA
GCGTCTGCGGGTCACGGTCAGCGGTCGCCCCGTCGCCGAGCTGGTCCCGTTGCCCAGCCGCCAGCCCAGCATGGCGTGGG
ATCACTTCGTGCGGCACATCTCCGGAGGGCTGGCAGACGCTGCGCTGGCCGACGATCTGGCCGCCCTCCTTCCCGACACC
ACCGACGACGTGCCCGTCCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References