Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/PIN(toxin) |
Location | 323059..323871 | Replicon | chromosome |
Accession | NC_016943 | ||
Organism | Blastococcus saxobsidens DD2 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | H6RM62 |
Locus tag | BLASA_RS01480 | Protein ID | WP_014374221.1 |
Coordinates | 323470..323871 (-) | Length | 134 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | H6RM61 |
Locus tag | BLASA_RS01475 | Protein ID | WP_014374220.1 |
Coordinates | 323059..323322 (-) | Length | 88 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BLASA_RS01445 | 319551..319895 | - | 345 | WP_041775541.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
BLASA_RS01450 | 319889..320137 | - | 249 | WP_041775983.1 | ribbon-helix-helix protein, CopG family | - |
BLASA_RS01455 | 320183..321244 | + | 1062 | WP_014374216.1 | 4Fe-4S dicluster domain-containing protein | - |
BLASA_RS01460 | 321247..322308 | + | 1062 | WP_014374217.1 | polysulfide reductase NrfD | - |
BLASA_RS01465 | 322423..322626 | + | 204 | WP_014374218.1 | hypothetical protein | - |
BLASA_RS01470 | 322652..323062 | - | 411 | WP_014374219.1 | type II toxin-antitoxin system VapC family toxin | - |
BLASA_RS01475 | 323059..323322 | - | 264 | WP_014374220.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
BLASA_RS01480 | 323470..323871 | - | 402 | WP_014374221.1 | ribonuclease | Toxin |
BLASA_RS01485 | 323868..324095 | - | 228 | WP_014374222.1 | hypothetical protein | - |
BLASA_RS01490 | 324487..324690 | + | 204 | WP_014374223.1 | hypothetical protein | - |
BLASA_RS01495 | 324760..325161 | - | 402 | WP_014374224.1 | type II toxin-antitoxin system VapC family toxin | - |
BLASA_RS01500 | 325158..325424 | - | 267 | WP_014374225.1 | ribbon-helix-helix protein, CopG family | - |
BLASA_RS01505 | 325508..326305 | - | 798 | WP_014374226.1 | hypothetical protein | - |
BLASA_RS01510 | 326307..326696 | - | 390 | WP_014374227.1 | S-adenosylmethionine decarboxylase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 294300..382307 | 88007 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 14338.21 Da Isoelectric Point: 5.8868
>T26132 WP_014374221.1 NC_016943:c323871-323470 [Blastococcus saxobsidens DD2]
MTVLLDANALTALTVADHVHHDLTEAWFTQRSEPFATCPVTQGALARFLLRGGATARQALDVVRALRAADGHEFWPDELG
YDVIDMRGVVGHRQVTDAYLAGLTRSRGGRLATFDRALAALHDDVAMLLDGGG
MTVLLDANALTALTVADHVHHDLTEAWFTQRSEPFATCPVTQGALARFLLRGGATARQALDVVRALRAADGHEFWPDELG
YDVIDMRGVVGHRQVTDAYLAGLTRSRGGRLATFDRALAALHDDVAMLLDGGG
Download Length: 402 bp
>T26132 NC_016943:c323871-323470 [Blastococcus saxobsidens DD2]
ATGACGGTCCTGCTCGACGCGAACGCACTCACCGCACTCACCGTCGCCGACCACGTCCACCACGACCTCACGGAGGCCTG
GTTCACGCAGCGATCGGAGCCCTTCGCGACCTGCCCCGTGACCCAGGGGGCACTCGCCCGATTCCTGCTCCGCGGCGGGG
CGACCGCGCGGCAGGCCCTCGATGTGGTGCGCGCCCTGCGAGCGGCGGATGGGCATGAGTTCTGGCCCGACGAACTCGGC
TACGACGTCATCGACATGCGCGGGGTGGTCGGGCACCGACAGGTGACCGACGCCTACCTGGCCGGGCTGACCCGCTCGCG
AGGCGGTCGACTGGCCACCTTCGACCGCGCCCTAGCAGCGCTCCACGATGACGTCGCGATGCTGCTCGACGGTGGCGGCT
GA
ATGACGGTCCTGCTCGACGCGAACGCACTCACCGCACTCACCGTCGCCGACCACGTCCACCACGACCTCACGGAGGCCTG
GTTCACGCAGCGATCGGAGCCCTTCGCGACCTGCCCCGTGACCCAGGGGGCACTCGCCCGATTCCTGCTCCGCGGCGGGG
CGACCGCGCGGCAGGCCCTCGATGTGGTGCGCGCCCTGCGAGCGGCGGATGGGCATGAGTTCTGGCCCGACGAACTCGGC
TACGACGTCATCGACATGCGCGGGGTGGTCGGGCACCGACAGGTGACCGACGCCTACCTGGCCGGGCTGACCCGCTCGCG
AGGCGGTCGACTGGCCACCTTCGACCGCGCCCTAGCAGCGCTCCACGATGACGTCGCGATGCTGCTCGACGGTGGCGGCT
GA
Antitoxin
Download Length: 88 a.a. Molecular weight: 9673.77 Da Isoelectric Point: 5.1409
>AT26132 WP_014374220.1 NC_016943:c323322-323059 [Blastococcus saxobsidens DD2]
MGLNIKNPETEELARQLADATGENLTRAITVAVRERLDRIQRRGTAAAADRTALLQRIAGDAADRWVEPYRSSDHGDLLY
DETGLPR
MGLNIKNPETEELARQLADATGENLTRAITVAVRERLDRIQRRGTAAAADRTALLQRIAGDAADRWVEPYRSSDHGDLLY
DETGLPR
Download Length: 264 bp
>AT26132 NC_016943:c323322-323059 [Blastococcus saxobsidens DD2]
ATGGGCCTCAACATCAAGAACCCGGAAACCGAGGAGCTCGCCCGCCAACTCGCCGACGCAACCGGCGAGAACCTCACGCG
GGCCATCACCGTGGCGGTGCGCGAACGTCTCGATCGGATTCAACGCCGGGGCACCGCCGCGGCGGCCGACCGCACCGCCC
TGCTCCAGAGGATTGCCGGGGATGCAGCCGATCGGTGGGTCGAGCCCTATCGCAGCAGCGACCACGGCGACCTGCTCTAC
GACGAGACCGGCCTGCCCCGATGA
ATGGGCCTCAACATCAAGAACCCGGAAACCGAGGAGCTCGCCCGCCAACTCGCCGACGCAACCGGCGAGAACCTCACGCG
GGCCATCACCGTGGCGGTGCGCGAACGTCTCGATCGGATTCAACGCCGGGGCACCGCCGCGGCGGCCGACCGCACCGCCC
TGCTCCAGAGGATTGCCGGGGATGCAGCCGATCGGTGGGTCGAGCCCTATCGCAGCAGCGACCACGGCGACCTGCTCTAC
GACGAGACCGGCCTGCCCCGATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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