Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2029146..2029291 Replicon chromosome
Accession NZ_CP107432
Organism Klebsiella pneumoniae strain CRKP_18

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2029182..2029284 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2029146..2029291 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH509_RS09935 2024276..2026336 + 2061 WP_004151449.1 oligopeptidase B -
OH509_RS09940 2026340..2026999 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH509_RS09945 2027078..2027308 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH509_RS09950 2027421..2027795 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH509_RS09955 2027799..2028668 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH509_RS09960 2028685..2029023 + 339 WP_002911404.1 YebY family protein -
- 2029146..2029291 - 146 - - Antitoxin
- 2029182..2029284 + 103 - - Toxin
OH509_RS09965 2029659..2029802 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH509_RS09970 2029907..2030875 - 969 WP_004151446.1 VirK/YbjX family protein -
OH509_RS09975 2031032..2031685 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH509_RS09980 2031682..2031873 - 192 WP_002911395.1 YebW family protein -
OH509_RS09985 2031971..2032210 - 240 WP_002911393.1 YebV family protein -
OH509_RS09990 2032326..2033759 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T261256 NZ_CP107432:2029182-2029284 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT261256 NZ_CP107432:c2029291-2029146 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References