Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 705246..705391 Replicon chromosome
Accession NZ_CP107426
Organism Klebsiella pneumoniae strain CRKP_19

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 705253..705355 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 705246..705391 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH521_RS03550 700778..702211 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OH521_RS03555 702327..702566 + 240 WP_002911393.1 YebV family protein -
OH521_RS03560 702664..702855 + 192 WP_002911395.1 YebW family protein -
OH521_RS03565 702852..703505 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH521_RS03570 703662..704630 + 969 WP_004151446.1 VirK/YbjX family protein -
OH521_RS03575 704735..704878 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 705246..705391 + 146 - - Antitoxin
- 705253..705355 - 103 - - Toxin
OH521_RS03580 705514..705852 - 339 WP_002911404.1 YebY family protein -
OH521_RS03585 705869..706738 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH521_RS03590 706742..707116 - 375 WP_004151448.1 CopC domain-containing protein YobA -
OH521_RS03595 707229..707459 + 231 WP_002911406.1 DNA polymerase III subunit theta -
OH521_RS03600 707538..708197 + 660 WP_002911407.1 exodeoxyribonuclease X -
OH521_RS03605 708201..710261 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T261226 NZ_CP107426:c705355-705253 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT261226 NZ_CP107426:705246-705391 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References