Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2023329..2023474 Replicon chromosome
Accession NZ_CP107417
Organism Klebsiella pneumoniae strain CRKP_21

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2023365..2023467 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2023329..2023474 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH498_RS09905 2018459..2020519 + 2061 WP_004151449.1 oligopeptidase B -
OH498_RS09910 2020523..2021182 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH498_RS09915 2021261..2021491 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH498_RS09920 2021604..2021978 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH498_RS09925 2021982..2022851 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH498_RS09930 2022868..2023206 + 339 WP_002911404.1 YebY family protein -
- 2023329..2023474 - 146 - - Antitoxin
- 2023365..2023467 + 103 - - Toxin
OH498_RS09935 2023842..2023985 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH498_RS09940 2024090..2025058 - 969 WP_004151446.1 VirK/YbjX family protein -
OH498_RS09945 2025215..2025868 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH498_RS09950 2025865..2026056 - 192 WP_002911395.1 YebW family protein -
OH498_RS09955 2026154..2026393 - 240 WP_002911393.1 YebV family protein -
OH498_RS09960 2026509..2027942 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T261183 NZ_CP107417:2023365-2023467 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT261183 NZ_CP107417:c2023474-2023329 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References