Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4756699..4756844 Replicon chromosome
Accession NZ_CP107403
Organism Klebsiella pneumoniae strain CRKP_25

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4756735..4756837 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4756699..4756844 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH516_RS23320 4751829..4753889 + 2061 WP_004151449.1 oligopeptidase B -
OH516_RS23325 4753893..4754552 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH516_RS23330 4754631..4754861 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH516_RS23335 4754974..4755348 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH516_RS23340 4755352..4756221 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH516_RS23345 4756238..4756576 + 339 WP_002911404.1 YebY family protein -
- 4756699..4756844 - 146 - - Antitoxin
- 4756735..4756837 + 103 - - Toxin
OH516_RS23350 4757212..4757355 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH516_RS23355 4757460..4758428 - 969 WP_004151446.1 VirK/YbjX family protein -
OH516_RS23360 4758585..4759238 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH516_RS23365 4759235..4759426 - 192 WP_002911395.1 YebW family protein -
OH516_RS23370 4759524..4759763 - 240 WP_002911393.1 YebV family protein -
OH516_RS23375 4759879..4761312 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T261119 NZ_CP107403:4756735-4756837 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT261119 NZ_CP107403:c4756844-4756699 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References