Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1983418..1983563 Replicon chromosome
Accession NZ_CP107398
Organism Klebsiella pneumoniae strain CRKP_26

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1983454..1983556 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1983418..1983563 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH520_RS09680 1978548..1980608 + 2061 WP_004151449.1 oligopeptidase B -
OH520_RS09685 1980612..1981271 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH520_RS09690 1981350..1981580 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH520_RS09695 1981693..1982067 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH520_RS09700 1982071..1982940 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH520_RS09705 1982957..1983295 + 339 WP_002911404.1 YebY family protein -
- 1983418..1983563 - 146 - - Antitoxin
- 1983454..1983556 + 103 - - Toxin
OH520_RS09710 1983931..1984074 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH520_RS09715 1984179..1985147 - 969 WP_004151446.1 VirK/YbjX family protein -
OH520_RS09720 1985304..1985957 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH520_RS09725 1985954..1986145 - 192 WP_002911395.1 YebW family protein -
OH520_RS09730 1986243..1986482 - 240 WP_002911393.1 YebV family protein -
OH520_RS09735 1986598..1988031 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T261088 NZ_CP107398:1983454-1983556 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT261088 NZ_CP107398:c1983563-1983418 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References