Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /DUF1778(antitoxin) |
| Location | 902859..903655 | Replicon | chromosome |
| Accession | NC_016901 | ||
| Organism | Shewanella baltica OS678 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | SBAL678_RS27225 | Protein ID | WP_014357899.1 |
| Coordinates | 903125..903655 (+) | Length | 177 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | B8ECY1 |
| Locus tag | SBAL678_RS27220 | Protein ID | WP_012586779.1 |
| Coordinates | 902859..903128 (+) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SBAL678_RS27195 | 898467..899141 | + | 675 | WP_006086056.1 | Fe2+-dependent dioxygenase | - |
| SBAL678_RS27200 | 899519..900628 | + | 1110 | WP_006079577.1 | ISAs1-like element ISSba2 family transposase | - |
| SBAL678_RS27205 | 900806..901291 | + | 486 | WP_014357896.1 | hypothetical protein | - |
| SBAL678_RS27210 | 901383..901970 | + | 588 | WP_014357897.1 | hypothetical protein | - |
| SBAL678_RS27215 | 902073..902696 | + | 624 | WP_014357898.1 | hypothetical protein | - |
| SBAL678_RS27220 | 902859..903128 | + | 270 | WP_012586779.1 | DUF1778 domain-containing protein | Antitoxin |
| SBAL678_RS27225 | 903125..903655 | + | 531 | WP_014357899.1 | GNAT family N-acetyltransferase | Toxin |
| SBAL678_RS27230 | 903999..904571 | + | 573 | WP_014357900.1 | hypothetical protein | - |
| SBAL678_RS27235 | 904568..904966 | + | 399 | WP_014357901.1 | hypothetical protein | - |
| SBAL678_RS27240 | 905062..905355 | + | 294 | WP_014357902.1 | hypothetical protein | - |
| SBAL678_RS27245 | 905416..906063 | + | 648 | WP_014357903.1 | DUF4145 domain-containing protein | - |
| SBAL678_RS27250 | 906112..906432 | - | 321 | WP_014357904.1 | hypothetical protein | - |
| SBAL678_RS27255 | 906429..906659 | - | 231 | WP_012089043.1 | hypothetical protein | - |
| SBAL678_RS27260 | 906656..906934 | - | 279 | WP_011847799.1 | hypothetical protein | - |
| SBAL678_RS27265 | 906935..907228 | - | 294 | WP_014357905.1 | hypothetical protein | - |
| SBAL678_RS27270 | 907225..907869 | - | 645 | WP_014357906.1 | hypothetical protein | - |
| SBAL678_RS27275 | 907866..908195 | - | 330 | WP_014357907.1 | hypothetical protein | - |
| SBAL678_RS47495 | 908206..908370 | - | 165 | WP_014357908.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 891750..944799 | 53049 | |
| - | flank | IS/Tn | - | - | 899519..900628 | 1109 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 177 a.a. Molecular weight: 19638.85 Da Isoelectric Point: 8.2341
>T26090 WP_014357899.1 NC_016901:903125-903655 [Shewanella baltica OS678]
VSYSKTFKELDKSQHDRASFDCGEAELNDFIQTQAAKHMQAGISRTMVLPAATPLPNQKYPICSFYTIAPSSICRDTLPQ
AMGKKLPRYPVPVFLLAQLAVHREFHGSGLGKASLIKALEYLWEINAHMRAYAIVVDCLTGQAESFYAKYGFEVLCEING
CVRMFIPIKTVGQLFP
VSYSKTFKELDKSQHDRASFDCGEAELNDFIQTQAAKHMQAGISRTMVLPAATPLPNQKYPICSFYTIAPSSICRDTLPQ
AMGKKLPRYPVPVFLLAQLAVHREFHGSGLGKASLIKALEYLWEINAHMRAYAIVVDCLTGQAESFYAKYGFEVLCEING
CVRMFIPIKTVGQLFP
Download Length: 531 bp
>T26090 NC_016901:903125-903655 [Shewanella baltica OS678]
GTGAGTTATTCCAAGACTTTTAAAGAATTGGATAAATCACAACACGATAGAGCATCATTTGACTGTGGCGAAGCAGAGTT
AAACGATTTTATCCAAACTCAAGCAGCGAAACACATGCAAGCAGGTATTAGCCGTACAATGGTTTTACCTGCTGCTACGC
CATTACCCAATCAAAAATATCCAATTTGCTCATTTTATACTATCGCACCAAGTTCAATTTGCCGTGATACCTTGCCGCAA
GCCATGGGTAAAAAGTTACCACGCTATCCCGTTCCGGTCTTTCTGCTTGCTCAACTTGCCGTCCATAGAGAGTTTCATGG
CAGTGGGCTAGGTAAAGCTAGTTTAATCAAAGCACTAGAATATCTTTGGGAAATTAACGCTCACATGAGAGCTTATGCCA
TTGTTGTCGATTGCTTAACTGGCCAAGCTGAATCATTTTACGCTAAGTATGGTTTCGAGGTTCTTTGTGAAATCAACGGT
TGTGTAAGAATGTTTATTCCAATAAAAACAGTCGGTCAGTTGTTCCCTTAG
GTGAGTTATTCCAAGACTTTTAAAGAATTGGATAAATCACAACACGATAGAGCATCATTTGACTGTGGCGAAGCAGAGTT
AAACGATTTTATCCAAACTCAAGCAGCGAAACACATGCAAGCAGGTATTAGCCGTACAATGGTTTTACCTGCTGCTACGC
CATTACCCAATCAAAAATATCCAATTTGCTCATTTTATACTATCGCACCAAGTTCAATTTGCCGTGATACCTTGCCGCAA
GCCATGGGTAAAAAGTTACCACGCTATCCCGTTCCGGTCTTTCTGCTTGCTCAACTTGCCGTCCATAGAGAGTTTCATGG
CAGTGGGCTAGGTAAAGCTAGTTTAATCAAAGCACTAGAATATCTTTGGGAAATTAACGCTCACATGAGAGCTTATGCCA
TTGTTGTCGATTGCTTAACTGGCCAAGCTGAATCATTTTACGCTAAGTATGGTTTCGAGGTTCTTTGTGAAATCAACGGT
TGTGTAAGAATGTTTATTCCAATAAAAACAGTCGGTCAGTTGTTCCCTTAG
Antitoxin
Download Length: 90 a.a. Molecular weight: 9903.38 Da Isoelectric Point: 4.9059
>AT26090 WP_012586779.1 NC_016901:902859-903128 [Shewanella baltica OS678]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVIAEHESITVKADVFDQFIMACDEAKAPNKALREAA
AFTKRGEFK
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVIAEHESITVKADVFDQFIMACDEAKAPNKALREAA
AFTKRGEFK
Download Length: 270 bp
>AT26090 NC_016901:902859-903128 [Shewanella baltica OS678]
ATGGCGACTGCAAGACTTGATATCCGTTTGGATGAAGAGATCAAAGCTAAGGCTGAGAAAGCATCGGCGTTGCTTGGTTT
AAAAAGCTTAACTGAATACGTTGTTCGCTTAATGGACGAAGATTCAACTCAGGTGATTGCTGAGCATGAAAGCATTACTG
TTAAAGCTGATGTATTCGACCAATTCATAATGGCTTGTGATGAGGCTAAGGCCCCGAACAAGGCATTGCGGGAAGCGGCA
GCATTTACTAAACGTGGTGAGTTTAAGTGA
ATGGCGACTGCAAGACTTGATATCCGTTTGGATGAAGAGATCAAAGCTAAGGCTGAGAAAGCATCGGCGTTGCTTGGTTT
AAAAAGCTTAACTGAATACGTTGTTCGCTTAATGGACGAAGATTCAACTCAGGTGATTGCTGAGCATGAAAGCATTACTG
TTAAAGCTGATGTATTCGACCAATTCATAATGGCTTGTGATGAGGCTAAGGCCCCGAACAAGGCATTGCGGGAAGCGGCA
GCATTTACTAAACGTGGTGAGTTTAAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|