Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4502406..4502551 Replicon chromosome
Accession NZ_CP107352
Organism Klebsiella pneumoniae strain CRKP_35

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4502442..4502544 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4502406..4502551 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH515_RS21620 4497536..4499596 + 2061 WP_004148850.1 oligopeptidase B -
OH515_RS21625 4499600..4500259 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH515_RS21630 4500338..4500568 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH515_RS21635 4500681..4501055 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH515_RS21640 4501059..4501928 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
OH515_RS21645 4501945..4502283 + 339 WP_002911404.1 YebY family protein -
- 4502406..4502551 - 146 - - Antitoxin
- 4502442..4502544 + 103 - - Toxin
OH515_RS21650 4502919..4503062 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH515_RS21655 4503167..4504135 - 969 WP_074195444.1 VirK/YbjX family protein -
OH515_RS21660 4504292..4504945 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH515_RS21665 4504942..4505133 - 192 WP_002911395.1 YebW family protein -
OH515_RS21670 4505231..4505470 - 240 WP_002911393.1 YebV family protein -
OH515_RS21675 4505586..4507019 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T260883 NZ_CP107352:4502442-4502544 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT260883 NZ_CP107352:c4502551-4502406 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References