Detailed information of TA system TA026087

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 158416..158890
• Replicon: chromosome
• Accession: NC_016894
• Organism: Acetobacterium woodii DSM 1030

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AWO_RS00735
• Protein ID: WP_041668032.1
• Coordinates: 158416..158676 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: AWO_RS00740
• Protein ID: WP_041668034.1
• Coordinates: 158678..158890 (-)
• Length: 71 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AWO_RS00720	156662..157426	-	765	WP_014354554.1	Rha family transcriptional regulator	-
AWO_RS19435	157779..157961	-	183	WP_169314658.1	hypothetical protein	-
AWO_RS00735	158416..158676	-	261	WP_041668032.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AWO_RS00740	158678..158890	-	213	WP_041668034.1	hypothetical protein	Antitoxin
AWO_RS00745	159024..159614	-	591	WP_014354556.1	recombinase family protein	-
AWO_RS00750	159919..160182	-	264	WP_041668038.1	helix-turn-helix domain-containing protein	-
AWO_RS00755	160467..160802	+	336	WP_014354557.1	hypothetical protein	-
AWO_RS00760	161369..162412	+	1044	WP_014354558.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	131193..169510	38317

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-86)

Antitoxin

• Protein of unknown function DUF6290 (1-68)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10087.74 Da
• Isoelectric Point: 9.4473

>T26087 WP_041668032.1 NC_016894:c158676-158416 [Acetobacterium woodii DSM 1030]
MFVVEFSDATLKKLKKMDRYQASILIGWIEKNLENCDNPRIHGKPLTANHSGKWRYRVGDYRILALIEDDKIKIVIIDVG
HRSEIY

Nucleotide

• Length: 261 bp

>T26087 NC_016894:c158676-158416 [Acetobacterium woodii DSM 1030]
ATGTTTGTTGTTGAATTTTCAGATGCAACTTTGAAAAAATTAAAGAAAATGGATCGCTATCAGGCATCAATCCTAATTGG
ATGGATTGAAAAAAATCTTGAAAACTGCGATAATCCTAGGATTCATGGCAAACCACTAACAGCAAACCATAGTGGAAAAT
GGCGATATCGTGTTGGTGATTATCGGATTCTTGCACTCATAGAAGACGACAAAATAAAAATTGTTATCATCGATGTTGGT
CATCGGAGTGAAATATATTAA

Antitoxin

Protein

• Length: 71 a.a.
• Molecular weight: 8143.42 Da
• Isoelectric Point: 4.8359

>AT26087 WP_041668034.1 NC_016894:c158890-158678 [Acetobacterium woodii DSM 1030]
MSTISIRLSDKEDLLVRNYAKMHRLSVSDLVRASVIEKIEDEIDLKTFDEVLNKMEKTYSLDEVKKELGL

Nucleotide

• Length: 213 bp

>AT26087 NC_016894:c158890-158678 [Acetobacterium woodii DSM 1030]
ATGAGTACCATTTCTATTCGTCTTTCTGACAAAGAAGATTTGCTGGTTCGAAACTATGCCAAAATGCATAGATTATCTGT
TTCCGATTTGGTCAGAGCTTCAGTCATCGAAAAAATCGAGGATGAAATTGATTTAAAGACTTTCGATGAAGTCCTGAACA
AGATGGAAAAAACCTATTCTCTTGATGAAGTCAAGAAAGAATTAGGCTTGTAA