Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2009722..2009867 Replicon chromosome
Accession NZ_CP107345
Organism Klebsiella pneumoniae strain CRKP_36

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2009758..2009860 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2009722..2009867 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH497_RS09870 2004852..2006912 + 2061 WP_004151449.1 oligopeptidase B -
OH497_RS09875 2006916..2007575 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH497_RS09880 2007654..2007884 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH497_RS09885 2007997..2008371 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH497_RS09890 2008375..2009244 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH497_RS09895 2009261..2009599 + 339 WP_002911404.1 YebY family protein -
- 2009722..2009867 - 146 - - Antitoxin
- 2009758..2009860 + 103 - - Toxin
OH497_RS09900 2010235..2010378 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH497_RS09905 2010483..2011451 - 969 WP_004151446.1 VirK/YbjX family protein -
OH497_RS09910 2011608..2012261 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH497_RS09915 2012258..2012449 - 192 WP_002911395.1 YebW family protein -
OH497_RS09920 2012547..2012786 - 240 WP_002911393.1 YebV family protein -
OH497_RS09925 2012902..2014335 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T260850 NZ_CP107345:2009758-2009860 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT260850 NZ_CP107345:c2009867-2009722 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References