Detailed information of TA system TA026085

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 68279..68904
• Replicon: plasmid pSTUK-100
• Accession: NC_016864
• Organism: Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: STMUK_RS23650
• Protein ID: WP_000911322.1
• Coordinates: 68279..68677 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: STMUK_RS23655
• Protein ID: WP_000450265.1
• Coordinates: 68677..68904 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
STMUK_RS23635	64470..64964	+	495	WP_010999946.1	entry exclusion protein	-
STMUK_RS23640	65000..65731	+	732	WP_000782438.1	complement resistance protein TraT	-
STMUK_RS23645	66108..68270	+	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
STMUK_RS23650	68279..68677	-	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
STMUK_RS23655	68677..68904	-	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..93277	93277

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Haemolysin expression modulating, HHA (8-64)

Antitoxin

• Biofilm formation regulator YbaJ (1-118)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T26085 WP_000911322.1 NC_016864:c68677-68279 [Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T26085 NC_016864:c68677-68279 [Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT26085 WP_000450265.1 NC_016864:c68904-68677 [Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1]
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Nucleotide

• Length: 228 bp

>AT26085 NC_016864:c68904-68677 [Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1]
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