Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4749873..4750018 Replicon chromosome
Accession NZ_CP107312
Organism Klebsiella pneumoniae strain CRKP_41

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4749909..4750011 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4749873..4750018 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH506_RS23355 4745003..4747063 + 2061 WP_004151449.1 oligopeptidase B -
OH506_RS23360 4747067..4747726 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH506_RS23365 4747805..4748035 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH506_RS23370 4748148..4748522 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH506_RS23375 4748526..4749395 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH506_RS23380 4749412..4749750 + 339 WP_002911404.1 YebY family protein -
- 4749873..4750018 - 146 - - Antitoxin
- 4749909..4750011 + 103 - - Toxin
OH506_RS23385 4750386..4750529 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH506_RS23390 4750634..4751602 - 969 WP_004151446.1 VirK/YbjX family protein -
OH506_RS23395 4751759..4752412 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH506_RS23400 4752409..4752600 - 192 WP_002911395.1 YebW family protein -
OH506_RS23405 4752698..4752937 - 240 WP_002911393.1 YebV family protein -
OH506_RS23410 4753053..4754486 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T260732 NZ_CP107312:4749909-4750011 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT260732 NZ_CP107312:c4750018-4749873 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References