Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2044342..2044487 Replicon chromosome
Accession NZ_CP107308
Organism Klebsiella pneumoniae strain CRKP_42

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2044378..2044480 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2044342..2044487 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH538_RS10010 2039472..2041532 + 2061 WP_004151449.1 oligopeptidase B -
OH538_RS10015 2041536..2042195 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH538_RS10020 2042274..2042504 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH538_RS10025 2042617..2042991 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH538_RS10030 2042995..2043864 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH538_RS10035 2043881..2044219 + 339 WP_002911404.1 YebY family protein -
- 2044342..2044487 - 146 - - Antitoxin
- 2044378..2044480 + 103 - - Toxin
OH538_RS10040 2044855..2044998 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH538_RS10045 2045103..2046071 - 969 WP_004151446.1 VirK/YbjX family protein -
OH538_RS10050 2046228..2046881 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH538_RS10055 2046878..2047069 - 192 WP_002911395.1 YebW family protein -
OH538_RS10060 2047167..2047406 - 240 WP_002911393.1 YebV family protein -
OH538_RS10065 2047522..2048955 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T260704 NZ_CP107308:2044378-2044480 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT260704 NZ_CP107308:c2044487-2044342 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References