Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2162208..2162353 Replicon chromosome
Accession NZ_CP107297
Organism Klebsiella pneumoniae strain CRKP_44

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2162215..2162317 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2162208..2162353 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH517_RS11080 2157740..2159173 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OH517_RS11085 2159289..2159528 + 240 WP_002911393.1 YebV family protein -
OH517_RS11090 2159626..2159817 + 192 WP_002911395.1 YebW family protein -
OH517_RS11095 2159814..2160467 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH517_RS11100 2160624..2161592 + 969 WP_004151446.1 VirK/YbjX family protein -
OH517_RS11105 2161697..2161840 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2162208..2162353 + 146 - - Antitoxin
- 2162215..2162317 - 103 - - Toxin
OH517_RS11110 2162476..2162814 - 339 WP_002911404.1 YebY family protein -
OH517_RS11115 2162831..2163700 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH517_RS11120 2163704..2164078 - 375 WP_004151448.1 CopC domain-containing protein YobA -
OH517_RS11125 2164191..2164421 + 231 WP_002911406.1 DNA polymerase III subunit theta -
OH517_RS11130 2164500..2165159 + 660 WP_002911407.1 exodeoxyribonuclease X -
OH517_RS11135 2165163..2167223 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T260656 NZ_CP107297:c2162317-2162215 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT260656 NZ_CP107297:2162208-2162353 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References