Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 493036..493689 Replicon chromosome
Accession NZ_CP107289
Organism Acinetobacter pittii strain BM4623

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OFU58_RS02410 Protein ID WP_119685828.1
Coordinates 493300..493689 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A009HHW9
Locus tag OFU58_RS02405 Protein ID WP_002117064.1
Coordinates 493036..493293 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OFU58_RS02385 (OFU58_02385) 488549..489556 + 1008 WP_002116730.1 DNA-directed RNA polymerase subunit alpha -
OFU58_RS02390 (OFU58_02390) 489575..489952 + 378 WP_002049717.1 50S ribosomal protein L17 -
OFU58_RS02395 (OFU58_02395) 490134..491624 + 1491 WP_075384069.1 NAD(P)/FAD-dependent oxidoreductase -
OFU58_RS02400 (OFU58_02400) 491675..492847 - 1173 WP_068929632.1 acyl-CoA dehydrogenase family protein -
OFU58_RS02405 (OFU58_02405) 493036..493293 + 258 WP_002117064.1 succinate dehydrogenase assembly factor 2 Antitoxin
OFU58_RS02410 (OFU58_02410) 493300..493689 + 390 WP_119685828.1 hypothetical protein Toxin
OFU58_RS02415 (OFU58_02415) 494460..495548 + 1089 WP_014207738.1 hypothetical protein -
OFU58_RS02420 (OFU58_02420) 495633..496208 + 576 WP_005078319.1 rhombosortase -
OFU58_RS02425 (OFU58_02425) 496388..498583 + 2196 WP_017400431.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15456.55 Da        Isoelectric Point: 8.7390

>T260627 WP_119685828.1 NZ_CP107289:493300-493689 [Acinetobacter pittii]
MIKELNFELKYSRVSVIFQLFVGLGLAILLYQLLTPMWWLCAVVLLFIGFIFFLKQAQISQIEYLDQKLWSVAYFSEKEI
YRAEITKIIDYQLFVVLYFEGGPTKIAIVWFDQLPIQQWKRLKVLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10295.73 Da        Isoelectric Point: 4.4809

>AT260627 WP_002117064.1 NZ_CP107289:493036-493293 [Acinetobacter pittii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A009HHW9

References