260582

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-YafN
Location 69837..70359 Replicon plasmid unnamed2
Accession NZ_CP107263
Organism Leclercia adecarboxylata strain 2022CK-00320

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag N5937_RS24765 Protein ID WP_213802913.1
Coordinates 70075..70359 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID -
Locus tag N5937_RS24760 Protein ID WP_213802912.1
Coordinates 69837..70085 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5937_RS24735 (N5937_24740) 65474..66727 + 1254 WP_263951682.1 lactose permease -
N5937_RS24740 (N5937_24745) 66793..66933 + 141 Protein_57 galactoside O-acetyltransferase -
N5937_RS24755 (N5937_24760) 68668..69216 + 549 WP_263951685.1 hypothetical protein -
N5937_RS24760 (N5937_24765) 69837..70085 + 249 WP_213802912.1 plasmid stabilization protein Antitoxin
N5937_RS24765 (N5937_24770) 70075..70359 + 285 WP_213802913.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5937_RS24770 (N5937_24775) 70402..71717 - 1316 Protein_63 ISNCY family transposase -
N5937_RS24775 (N5937_24780) 72012..72232 - 221 Protein_64 arsenate reductase -
N5937_RS24780 (N5937_24785) 72513..73052 + 540 Protein_65 DUF4113 domain-containing protein -
N5937_RS24785 (N5937_24790) 73399..74370 - 972 WP_213802914.1 ParB/RepB/Spo0J family plasmid partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..93413 93413
- flank IS/Tn - - 67029..67322 293


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11063.83 Da        Isoelectric Point: 10.5388

>T260582 WP_213802913.1 NZ_CP107263:70075-70359 [Leclercia adecarboxylata]
MTYKLAFNESALKEWKKLGHTLQMQFKKKLKERLENPRVPASQLHGRKDQYKIKLRGAGYRLVYRVEDDIVTVTVIGVGK
RENDDIYNVTLNRN

Download         Length: 285 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9065.33 Da        Isoelectric Point: 3.9947

>AT260582 WP_213802912.1 NZ_CP107263:69837-70085 [Leclercia adecarboxylata]
MAFQVLTTTAASITELKRDPMGTFHAGDGAPVAILNRNEPAFYCVPPALYAQLMELLEDEELGRMADERIGERVIEVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References