Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3515999..3516659 Replicon chromosome
Accession NZ_CP107262
Organism Leclercia adecarboxylata strain 2022CK-00320

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag N5937_RS17425 Protein ID WP_103176874.1
Coordinates 3516246..3516659 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag N5937_RS17420 Protein ID WP_103176875.1
Coordinates 3515999..3516265 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5937_RS17395 (3511161) 3511161..3512594 - 1434 WP_156655195.1 6-phospho-beta-glucosidase BglA -
N5937_RS17400 (3512709) 3512709..3513440 - 732 WP_103176879.1 MurR/RpiR family transcriptional regulator -
N5937_RS17405 (3513493) 3513493..3513804 + 312 WP_103176878.1 N(4)-acetylcytidine aminohydrolase -
N5937_RS17410 (3513970) 3513970..3514629 + 660 WP_103176877.1 hemolysin III family protein -
N5937_RS17415 (3514715) 3514715..3515695 - 981 WP_156655194.1 tRNA-modifying protein YgfZ -
N5937_RS17420 (3515999) 3515999..3516265 + 267 WP_103176875.1 FAD assembly factor SdhE Antitoxin
N5937_RS17425 (3516246) 3516246..3516659 + 414 WP_103176874.1 protein YgfX Toxin
N5937_RS17430 (3516664) 3516664..3517185 - 522 WP_103176873.1 flavodoxin FldB -
N5937_RS17435 (3517286) 3517286..3518182 + 897 WP_214422374.1 site-specific tyrosine recombinase XerD -
N5937_RS17440 (3518204) 3518204..3518917 + 714 WP_263950284.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N5937_RS17445 (3518923) 3518923..3520656 + 1734 WP_103176870.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16236.07 Da        Isoelectric Point: 10.7511

>T260577 WP_103176874.1 NZ_CP107262:3516246-3516659 [Leclercia adecarboxylata]
VVLWQSDLRVSWRAQWMSLLLHGLVAAVILLMPWPLSYTPLWLMLLSLVVFDSVRSQRRINARQGEIKLFMDSRLHWQES
EWEIVGTPWMLNSGMMLRLRKGAGQRCHHLWLAADSMDEAEWRDLRRMMSHQPTQGR

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10503.97 Da        Isoelectric Point: 4.8382

>AT260577 WP_103176875.1 NZ_CP107262:3515999-3516265 [Leclercia adecarboxylata]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDEDKHLFVRLLENDDPDLFNWLMNHGKPADAELQRMVLLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References