260573

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 2179123..2179639 Replicon chromosome
Accession NZ_CP107262
Organism Leclercia adecarboxylata strain 2022CK-00320

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N5937_RS11005 Protein ID WP_103178030.1
Coordinates 2179123..2179407 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N5937_RS11010 Protein ID WP_103178029.1
Coordinates 2179397..2179639 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5937_RS10990 (2174384) 2174384..2176039 + 1656 WP_263951550.1 alpha,alpha-phosphotrehalase -
N5937_RS10995 (2176410) 2176410..2178548 + 2139 WP_263951551.1 anaerobic ribonucleoside-triphosphate reductase -
N5937_RS11000 (2178655) 2178655..2179119 + 465 WP_263951552.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
N5937_RS11005 (2179123) 2179123..2179407 - 285 WP_103178030.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5937_RS11010 (2179397) 2179397..2179639 - 243 WP_103178029.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N5937_RS11015 (2179717) 2179717..2181627 - 1911 WP_159340183.1 PRD domain-containing protein -
N5937_RS11020 (2181647) 2181647..2182783 - 1137 WP_263951554.1 lactonase family protein -
N5937_RS11025 (2182838) 2182838..2183578 - 741 WP_263951555.1 KDGP aldolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-65)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10898.68 Da        Isoelectric Point: 10.4610

>T260573 WP_103178030.1 NZ_CP107262:c2179407-2179123 [Leclercia adecarboxylata]
MTYELEFDPRALKEWQKLGDTVKSQFKKKLAVVLSNPRRESARLHGLPDCYKIKLSSSGYRLVYQVRDKVITVFVVAVGK
REKSAVYHDANQRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9057.44 Da        Isoelectric Point: 5.1088

>AT260573 WP_103178029.1 NZ_CP107262:c2179639-2179397 [Leclercia adecarboxylata]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAENGRMPVKTVTVSDSEDELIRTVRERLANPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References