Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2460183..2460850 Replicon chromosome
Accession NZ_CP107244
Organism Achromobacter sp. SS2-2022

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N3Z32_RS11125 Protein ID WP_268077631.1
Coordinates 2460183..2460602 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N3Z32_RS11130 Protein ID WP_268077632.1
Coordinates 2460599..2460850 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N3Z32_RS11100 (N3Z32_11100) 2455937..2456896 - 960 WP_268077626.1 DMT family transporter -
N3Z32_RS11105 (N3Z32_11105) 2456978..2457847 - 870 WP_268077627.1 AraC family transcriptional regulator -
N3Z32_RS11110 (N3Z32_11110) 2457934..2459208 - 1275 WP_268077628.1 RNA polymerase sigma factor -
N3Z32_RS11115 (N3Z32_11115) 2459205..2459612 - 408 WP_268077629.1 VOC family protein -
N3Z32_RS11120 (N3Z32_11120) 2459631..2460041 - 411 WP_268077630.1 YciI family protein -
N3Z32_RS11125 (N3Z32_11125) 2460183..2460602 - 420 WP_268077631.1 type II toxin-antitoxin system VapC family toxin Toxin
N3Z32_RS11130 (N3Z32_11130) 2460599..2460850 - 252 WP_268077632.1 Arc family DNA-binding protein Antitoxin
N3Z32_RS11135 (N3Z32_11135) 2460951..2461304 - 354 WP_268077633.1 YciI family protein -
N3Z32_RS11140 (N3Z32_11140) 2461468..2462451 - 984 WP_268077634.1 OmpA family protein -
N3Z32_RS11145 (N3Z32_11145) 2462448..2463347 - 900 WP_268077635.1 MotA/TolQ/ExbB proton channel family protein -
N3Z32_RS11150 (N3Z32_11150) 2463645..2465612 + 1968 WP_268077636.1 NYN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin

Arc-like DNA binding domain

(10-46)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14660.88 Da        Isoelectric Point: 4.8181

>T260557 WP_268077631.1 NZ_CP107244:c2460602-2460183 [Achromobacter sp. SS2-2022]
MILLDTNVISEPLRQAPADAVIEWIDRQPLETLFLSAVTVAELRFGVACMPVGKRRDALHGDLEQRVLALFAGRILAFDT
SASLEYVALMARARASGQAIGGPDGYIAATAAAHGMSVATRDVAPFEAAGVSVINPWGA

Download         Length: 420 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9284.64 Da        Isoelectric Point: 8.9326

>AT260557 WP_268077632.1 NZ_CP107244:c2460850-2460599 [Achromobacter sp. SS2-2022]
MPMLTVRNISEEVHRALRVRAAQHGRSTEAEVRAILEDAVKPEGRVKLGSLLLQIGRQARLTDEEAALFDQRDKAPAAPP
RFE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References