Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 255143..255657 Replicon chromosome
Accession NZ_CP107244
Organism Achromobacter sp. SS2-2022

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N3Z32_RS01155 Protein ID WP_268080880.1
Coordinates 255143..255352 (+) Length 70 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N3Z32_RS01160 Protein ID WP_268080881.1
Coordinates 255349..255657 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N3Z32_RS01135 (N3Z32_01135) 250649..251665 + 1017 WP_268080876.1 amino acid ABC transporter substrate-binding protein -
N3Z32_RS01140 (N3Z32_01140) 251791..252981 + 1191 WP_268080877.1 amino acid ABC transporter permease -
N3Z32_RS01145 (N3Z32_01145) 252983..254083 + 1101 WP_268080878.1 amino acid ABC transporter permease -
N3Z32_RS01150 (N3Z32_01150) 254144..254884 + 741 WP_268080879.1 amino acid ABC transporter ATP-binding protein -
N3Z32_RS01155 (N3Z32_01155) 255143..255352 + 210 WP_268080880.1 hypothetical protein Toxin
N3Z32_RS01160 (N3Z32_01160) 255349..255657 + 309 WP_268080881.1 putative addiction module antidote protein Antitoxin
N3Z32_RS01165 (N3Z32_01165) 255777..256808 + 1032 WP_277550000.1 tripartite tricarboxylate transporter substrate binding protein -
N3Z32_RS01170 (N3Z32_01170) 257230..258405 - 1176 WP_268080883.1 ABC transporter substrate-binding protein -
N3Z32_RS01175 (N3Z32_01175) 258452..259684 - 1233 WP_268080884.1 3-hydroxybenzoate 6-monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-62)

Antitoxin

Cro/C1-type helix-turn-helix domain

(44-91)


Sequences

Toxin        


Download         Length: 70 a.a.        Molecular weight: 7693.76 Da        Isoelectric Point: 7.9936

>T260554 WP_268080880.1 NZ_CP107244:255143-255352 [Achromobacter sp. SS2-2022]
MHGNFGDVEAVGEGVSEMRVSIGAGYRLYYARADELVYVLLCGGDKTSQARDIARAKRLWTDIKRSIEK

Download         Length: 210 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11085.49 Da        Isoelectric Point: 6.4652

>AT260554 WP_268080881.1 NZ_CP107244:255349-255657 [Achromobacter sp. SS2-2022]
MSKLRDFDAANYLKDDETIAHYLADAAAEDDPDAFLQALGDVARARGITEIARETGLARTNLYRVLAPGANPSYHTLRKV
MNALGVSLTALVRRKSDPTPQG

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References