Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 5162730..5163095 Replicon chromosome
Accession NZ_CP107241
Organism Xanthomonas hortorum strain Oregano 108

Toxin (Protein)


Gene name EcnB Uniprot ID V7Z935
Locus tag OEG85_RS22280 Protein ID WP_006451341.1
Coordinates 5162730..5162864 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag OEG85_RS22285 Protein ID WP_006451340.1
Coordinates 5162943..5163095 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEG85_RS22265 (OEG85_22260) 5159677..5160663 - 987 WP_268213078.1 MBL fold metallo-hydrolase -
OEG85_RS22270 (OEG85_22265) 5160815..5162104 - 1290 WP_268213079.1 tryptophan--tRNA ligase -
OEG85_RS22275 (OEG85_22270) 5162278..5162487 - 210 WP_006451342.1 CsbD family protein -
OEG85_RS22280 (OEG85_22275) 5162730..5162864 - 135 WP_006451341.1 entericidin A/B family lipoprotein Toxin
OEG85_RS22285 (OEG85_22280) 5162943..5163095 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
OEG85_RS22290 (OEG85_22285) 5163205..5164128 - 924 WP_268213080.1 arginase -
OEG85_RS22295 (OEG85_22290) 5164591..5165043 + 453 WP_268213082.1 roadblock/LC7 domain-containing protein -
OEG85_RS22300 (OEG85_22295) 5165107..5165466 + 360 WP_006452081.1 hypothetical protein -
OEG85_RS22305 (OEG85_22300) 5165560..5166477 + 918 WP_268213083.1 hypothetical protein -
OEG85_RS22310 (OEG85_22305) 5166474..5167016 + 543 WP_268213084.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4493.34 Da        Isoelectric Point: 9.3487

>T260552 WP_006451341.1 NZ_CP107241:c5162864-5162730 [Xanthomonas hortorum]
MKRAIMLLVLSVFSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT260552 WP_006451340.1 NZ_CP107241:c5163095-5162943 [Xanthomonas hortorum]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7EZD1

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References