Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 4917802..4918415 Replicon chromosome
Accession NZ_CP107241
Organism Xanthomonas hortorum strain Oregano 108

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OEG85_RS21235 Protein ID WP_268212924.1
Coordinates 4918116..4918415 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OEG85_RS21230 Protein ID WP_268212923.1
Coordinates 4917802..4918119 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEG85_RS21210 (OEG85_21205) 4913831..4914193 - 363 WP_223647394.1 hypothetical protein -
OEG85_RS21215 (OEG85_21210) 4914331..4916076 - 1746 WP_268212921.1 ATP-binding protein -
OEG85_RS21220 (OEG85_21215) 4916073..4917329 - 1257 WP_223647390.1 SIR2 family protein -
OEG85_RS21225 (OEG85_21220) 4917434..4917646 - 213 WP_268212922.1 hypothetical protein -
OEG85_RS21230 (OEG85_21225) 4917802..4918119 - 318 WP_268212923.1 putative addiction module antidote protein Antitoxin
OEG85_RS21235 (OEG85_21230) 4918116..4918415 - 300 WP_268212924.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OEG85_RS21240 (OEG85_21235) 4918618..4918818 + 201 WP_268215220.1 antitoxin VbhA family protein -
OEG85_RS21245 (OEG85_21240) 4918863..4919967 + 1105 Protein_4165 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4899182..4935072 35890


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(11-98)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11219.92 Da        Isoelectric Point: 9.5610

>T260551 WP_268212924.1 NZ_CP107241:c4918415-4918116 [Xanthomonas hortorum]
MAYTVKQLDEFSGWLRGLKDGLTRQRLIKRLRKVQLGNLGDVEPVGEGVFEMREHFGPGWRMYYVQHGELVIVMLGGGDK
STQQADIRRATALAKSLED

Download         Length: 300 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11336.96 Da        Isoelectric Point: 4.6909

>AT260551 WP_268212923.1 NZ_CP107241:c4918119-4917802 [Xanthomonas hortorum]
MTMTKKIKVSELSEFDAAEYLNDEEDVAAYLTTVLEENDSALLAAALGDIARARGMSQVAKEAGIAREALYKALRPGSEP
RFETISRVCAALGVRLVAQPIHLAN

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References