Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 4218568..4219073 Replicon chromosome
Accession NZ_CP107241
Organism Xanthomonas hortorum strain Oregano 108

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OEG85_RS17965 Protein ID WP_268212529.1
Coordinates 4218816..4219073 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID F0BZS9
Locus tag OEG85_RS17960 Protein ID WP_006448404.1
Coordinates 4218568..4218819 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEG85_RS17940 (OEG85_17935) 4213941..4215095 - 1155 WP_268212524.1 2-methylcitrate synthase -
OEG85_RS17945 (OEG85_17940) 4215171..4216067 - 897 WP_268212525.1 methylisocitrate lyase -
OEG85_RS17950 (OEG85_17945) 4216195..4217814 + 1620 WP_268212527.1 propionate catabolism operon regulatory protein PrpR -
OEG85_RS17955 (OEG85_17950) 4218057..4218383 - 327 WP_006448403.1 hypothetical protein -
OEG85_RS17960 (OEG85_17955) 4218568..4218819 + 252 WP_006448404.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OEG85_RS17965 (OEG85_17960) 4218816..4219073 + 258 WP_268212529.1 Txe/YoeB family addiction module toxin Toxin
OEG85_RS17975 (OEG85_17970) 4219607..4219960 - 354 WP_003483889.1 PilZ domain-containing protein -
OEG85_RS17980 (OEG85_17975) 4219957..4220916 - 960 WP_176339478.1 DNA polymerase III subunit delta' -
OEG85_RS17985 (OEG85_17980) 4220913..4221964 - 1052 Protein_3537 endolytic transglycosylase MltG -
OEG85_RS17990 (OEG85_17985) 4222037..4223392 - 1356 WP_268212531.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10156.66 Da        Isoelectric Point: 9.6587

>T260550 WP_268212529.1 NZ_CP107241:4218816-4219073 [Xanthomonas hortorum]
VILQFADNAWEDYLYWQQTDKKMLKRINELIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRVVYKAENGILLIAQA
RYHYA

Download         Length: 258 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.48 Da        Isoelectric Point: 4.6536

>AT260550 WP_006448404.1 NZ_CP107241:4218568-4218819 [Xanthomonas hortorum]
MDTITYSAARASLADTMDRVVNDHEPVIITRSGERAVVMVSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKERE
LAE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0G8MAJ7

References