Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 4380160..4380745 Replicon chromosome
Accession NZ_CP107077
Organism Kosakonia cowanii strain LT-1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag ODS25_RS20510 Protein ID WP_128483861.1
Coordinates 4380160..4380450 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag ODS25_RS20515 Protein ID WP_042712602.1
Coordinates 4380467..4380745 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ODS25_RS20480 4375180..4376766 + 1587 WP_200134477.1 RNA repair transcriptional activator RtcR -
ODS25_RS20485 4376916..4377857 + 942 WP_128483859.1 ketopantoate/pantoate/pantothenate transporter PanS -
ODS25_RS20490 4377911..4378249 - 339 WP_042712607.1 XRE family transcriptional regulator -
ODS25_RS20495 4378236..4378601 - 366 WP_263753505.1 type II toxin-antitoxin system RelE/ParE family toxin -
ODS25_RS20500 4378777..4379049 + 273 WP_042712605.1 DUF3811 domain-containing protein -
ODS25_RS20505 4379050..4379919 - 870 WP_094419107.1 23S rRNA pseudouridine(2604) synthase RluF -
ODS25_RS20510 4380160..4380450 + 291 WP_128483861.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ODS25_RS20515 4380467..4380745 + 279 WP_042712602.1 putative addiction module antidote protein Antitoxin
ODS25_RS20520 4380774..4382405 - 1632 WP_124970715.1 Na/Pi cotransporter family protein -
ODS25_RS20525 4382577..4383005 - 429 WP_263753506.1 hypothetical protein -
ODS25_RS20530 4383028..4383804 - 777 WP_094419106.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(28-82)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10719.56 Da        Isoelectric Point: 9.9480

>T260515 WP_128483861.1 NZ_CP107077:4380160-4380450 [Kosakonia cowanii]
MKEIVQTDAFKLWESSLRDAKLRAIISARLFRLANGLTGDVKPVGEGISELRIHYGAGYRIYFQLRGNTVVVLLCGGDKS
TQPKDIIYAKYLAKCV

Download         Length: 291 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 9818.36 Da        Isoelectric Point: 6.2978

>AT260515 WP_042712602.1 NZ_CP107077:4380467-4380745 [Kosakonia cowanii]
MNKLTPYDPAAALVNDEAIALFMADALETGDAAYIARALGVIARAKGMSDIAAETGLSREQLYRSFSEKGNPTLKTTLSV
MKALGIELTVKR

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References