Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4126940..4127456 Replicon chromosome
Accession NZ_CP107077
Organism Kosakonia cowanii strain LT-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ODS25_RS19365 Protein ID WP_042714048.1
Coordinates 4126940..4127224 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ODS25_RS19370 Protein ID WP_042714051.1
Coordinates 4127214..4127456 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ODS25_RS19350 4122811..4123755 + 945 WP_263753380.1 trehalose operon repressor TreR -
ODS25_RS19355 4124103..4126238 + 2136 WP_263753381.1 anaerobic ribonucleoside-triphosphate reductase -
ODS25_RS19360 4126470..4126934 + 465 WP_094422771.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
ODS25_RS19365 4126940..4127224 - 285 WP_042714048.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ODS25_RS19370 4127214..4127456 - 243 WP_042714051.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
ODS25_RS19375 4127535..4129445 - 1911 WP_263753385.1 BglG family transcription antiterminator -
ODS25_RS19380 4129526..4130263 - 738 WP_263753386.1 KDGP aldolase family protein -
ODS25_RS19385 4130260..4131378 - 1119 WP_128483769.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-70)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10923.95 Da        Isoelectric Point: 10.5826

>T260514 WP_042714048.1 NZ_CP107077:c4127224-4126940 [Kosakonia cowanii]
MIYELVFDPRALKEWKKLGVTVQAQFKKKLAEVLVQPRVEKARLHGLPDCYKIKLRASGYRLIYQVRDNVVTVFVVAIGK
REKEAAYHSATHRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9133.62 Da        Isoelectric Point: 4.8537

>AT260514 WP_042714051.1 NZ_CP107077:c4127456-4127214 [Kosakonia cowanii]
MATLNVRLDDKLKEEAWKVLEKLDITPTEAVRLLFQYVAENGRMPVKTVTVSEDEAALLEVVRERLANPQKGIKVRLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References