Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 807795..808458 Replicon chromosome
Accession NZ_CP107077
Organism Kosakonia cowanii strain LT-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag ODS25_RS03765 Protein ID WP_042718300.1
Coordinates 808042..808458 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A807LAC0
Locus tag ODS25_RS03760 Protein ID WP_023480982.1
Coordinates 807795..808061 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ODS25_RS03740 803351..804784 - 1434 WP_124967325.1 6-phospho-beta-glucosidase -
ODS25_RS03745 804902..805630 - 729 WP_263754676.1 MurR/RpiR family transcriptional regulator -
ODS25_RS03750 805858..806517 + 660 WP_263753980.1 hemolysin III family protein -
ODS25_RS03755 806568..807548 - 981 WP_200134952.1 tRNA-modifying protein YgfZ -
ODS25_RS03760 807795..808061 + 267 WP_023480982.1 FAD assembly factor SdhE Antitoxin
ODS25_RS03765 808042..808458 + 417 WP_042718300.1 protein YgfX Toxin
ODS25_RS03770 808476..808997 - 522 WP_094422004.1 flavodoxin FldB -
ODS25_RS03775 809097..809993 + 897 WP_263753982.1 site-specific tyrosine recombinase XerD -
ODS25_RS03780 810018..810728 + 711 WP_042718296.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
ODS25_RS03785 810734..812467 + 1734 WP_200134954.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16436.32 Da        Isoelectric Point: 10.7346

>T260508 WP_042718300.1 NZ_CP107077:808042-808458 [Kosakonia cowanii]
VVLWQSELRVSWRAQWLSLLLHGFVAALILLMPWPLSYTPVWLLLLSLVVFDSVRSQRRINACHGEIKLLMDSRLRWQGE
EWDIVGTPWMLRSGMILRLRREEDGRRQHLWLASDSMDAQEWRDLRRMILQKPAQGLH

Download         Length: 417 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10556.01 Da        Isoelectric Point: 5.6186

>AT260508 WP_023480982.1 NZ_CP107077:807795-808061 [Kosakonia cowanii]
MDITNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDDKRLFVRLLENDDPDLFNWLMNHGKPQDAELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A807LAC0

References