Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-YafN
Location 650294..650813 Replicon chromosome
Accession NZ_CP107077
Organism Kosakonia cowanii strain LT-1

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag ODS25_RS03135 Protein ID WP_054803376.1
Coordinates 650294..650575 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID -
Locus tag ODS25_RS03140 Protein ID WP_042717989.1
Coordinates 650565..650813 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ODS25_RS03110 645640..646272 + 633 WP_042718073.1 ADP-ribose diphosphatase -
ODS25_RS03115 646269..646691 + 423 WP_023480711.1 DUF1249 family protein -
ODS25_RS03120 646716..647543 + 828 WP_263753920.1 3',5'-cyclic-AMP phosphodiesterase -
ODS25_RS03125 647543..648118 + 576 WP_023480978.1 esterase YqiA -
ODS25_RS03130 648158..650050 + 1893 WP_042717986.1 DNA topoisomerase IV subunit B -
ODS25_RS03135 650294..650575 - 282 WP_054803376.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ODS25_RS03140 650565..650813 - 249 WP_042717989.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
ODS25_RS03145 650864..651739 - 876 WP_263753921.1 AraC family transcriptional regulator -
ODS25_RS03150 651905..653731 + 1827 WP_263753922.1 DUF2264 domain-containing protein -
ODS25_RS03155 653789..655048 + 1260 WP_263753923.1 oligosaccharide MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10928.74 Da        Isoelectric Point: 10.6500

>T260507 WP_054803376.1 NZ_CP107077:c650575-650294 [Kosakonia cowanii]
MTYKLAFNVSALKEWKKLGSTVREQFKKKLQERLENPRVPAAQLHGRKDQYKIKLRGAGYRLVYKVEEEIITVTVIGVGK
RENDEIYTATRFR

Download         Length: 282 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9097.37 Da        Isoelectric Point: 3.9490

>AT260507 WP_042717989.1 NZ_CP107077:c650813-650565 [Kosakonia cowanii]
MPFQILTTTAASITELKRDPMGTFNAGEGAPVAILNRNEPAFYCVPPALYARLMEMLEDEELGRIADERADEPTIEVKLD
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References