260476

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 5173916..5174619 Replicon chromosome
Accession NZ_CP107040
Organism Klebsiella oxytoca strain TYL-T1

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag NQA44_RS24150 Protein ID WP_049017155.1
Coordinates 5173916..5174257 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag NQA44_RS24155 Protein ID WP_196550622.1
Coordinates 5174278..5174619 (-) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQA44_RS24130 (NQA44_24130) 5170160..5170954 + 795 WP_196550621.1 DNA/RNA non-specific endonuclease -
NQA44_RS24135 (NQA44_24135) 5171243..5171566 + 324 WP_023320260.1 endoribonuclease SymE -
NQA44_RS24140 (NQA44_24140) 5171713..5172147 + 435 WP_023320259.1 VOC family protein -
NQA44_RS24145 (NQA44_24145) 5172650..5173657 - 1008 WP_049017154.1 restriction endonuclease -
NQA44_RS24150 (NQA44_24150) 5173916..5174257 - 342 WP_049017155.1 TA system toxin CbtA family protein Toxin
NQA44_RS24155 (NQA44_24155) 5174278..5174619 - 342 WP_196550622.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NQA44_RS24160 (NQA44_24160) 5174630..5175172 - 543 WP_196550623.1 DNA repair protein RadC -
NQA44_RS24165 (NQA44_24165) 5175185..5175628 - 444 WP_047365977.1 antirestriction protein -
NQA44_RS24170 (NQA44_24170) 5175659..5176480 - 822 WP_049017158.1 DUF932 domain-containing protein -
NQA44_RS24175 (NQA44_24175) 5176601..5177074 - 474 WP_049017159.1 hypothetical protein -
NQA44_RS24180 (NQA44_24180) 5177146..5177598 - 453 WP_077258843.1 hypothetical protein -
NQA44_RS24185 (NQA44_24185) 5177634..5178350 - 717 WP_048291793.1 WYL domain-containing protein -
NQA44_RS24190 (NQA44_24190) 5178594..5179469 - 876 WP_048291792.1 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5171713..5190873 19160


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(13-111)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12724.66 Da        Isoelectric Point: 6.4514

>T260476 WP_049017155.1 NZ_CP107040:c5174257-5173916 [Klebsiella oxytoca]
MKTLPATTPQAATLCLSPVAVWQMLLACLLEQHYGLTLNDTPFSDETVIQEHIDAGITLADAVNFLVEKYELVRIDRRGF
NWQEQSPYLRAVDILRARQATGLLKRNRISAAQ

Download         Length: 342 bp

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12810.54 Da        Isoelectric Point: 6.7344

>AT260476 WP_196550622.1 NZ_CP107040:c5174619-5174278 [Klebsiella oxytoca]
MKYTDSENDSFLKWGLNRNVTPCFVARLVQEGNRLHYLADRASITGKFSEAECLKLDVAFPHFISQMESMLATGEMNPRH
AHCVTLYHNGFTCEADTLGSCGYVYIAVYPTHR

Download         Length: 342 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References