Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3289301..3289446 Replicon chromosome
Accession NZ_CP107014
Organism Klebsiella pneumoniae strain K30821

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3289308..3289410 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3289301..3289446 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OF890_RS16645 (OF890_16645) 3284833..3286266 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OF890_RS16650 (OF890_16650) 3286382..3286621 + 240 WP_002911393.1 YebV family protein -
OF890_RS16655 (OF890_16655) 3286719..3286910 + 192 WP_002911395.1 YebW family protein -
OF890_RS16660 (OF890_16660) 3286907..3287560 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
OF890_RS16665 (OF890_16665) 3287717..3288685 + 969 WP_004151446.1 VirK/YbjX family protein -
OF890_RS16670 (OF890_16670) 3288790..3288933 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3289301..3289446 + 146 - - Antitoxin
- 3289308..3289410 - 103 - - Toxin
OF890_RS16675 (OF890_16675) 3289569..3289907 - 339 WP_002911404.1 YebY family protein -
OF890_RS16680 (OF890_16680) 3289924..3290793 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OF890_RS16685 (OF890_16685) 3290797..3291171 - 375 WP_004151448.1 CopC domain-containing protein YobA -
OF890_RS16690 (OF890_16690) 3291284..3291514 + 231 WP_002911406.1 DNA polymerase III subunit theta -
OF890_RS16695 (OF890_16695) 3291593..3292252 + 660 WP_002911407.1 exodeoxyribonuclease X -
OF890_RS16700 (OF890_16700) 3292256..3294316 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T260424 NZ_CP107014:c3289410-3289308 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT260424 NZ_CP107014:3289301-3289446 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References