Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2008621..2008766 Replicon chromosome
Accession NZ_CP107010
Organism Salmonella enterica subsp. enterica serovar Paratyphi B strain SZ21B23

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2008661..2008764 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2008621..2008766 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OF884_RS09565 2005047..2005745 - 699 WP_000944287.1 exodeoxyribonuclease X -
OF884_RS09570 2005769..2006425 - 657 WP_000100249.1 carbon-nitrogen hydrolase family protein -
OF884_RS09575 2006533..2006763 - 231 WP_000856224.1 DNA polymerase III subunit theta -
OF884_RS09580 2006901..2007275 + 375 WP_000168393.1 CopC domain-containing protein YobA -
OF884_RS09585 2007276..2008151 + 876 WP_000979706.1 copper homeostasis membrane protein CopD -
OF884_RS09590 2008168..2008521 + 354 WP_000722368.1 YebY family protein -
- 2008621..2008766 - 146 - - Antitoxin
- 2008661..2008764 + 104 - - Toxin
OF884_RS09595 2008894..2009736 - 843 Protein_1877 tyrosine-type recombinase/integrase -
OF884_RS09600 2009827..2010183 + 357 WP_000003145.1 hypothetical protein -
OF884_RS09605 2010137..2010343 + 207 Protein_1879 phage tail protein -
OF884_RS09610 2010515..2010670 + 156 Protein_1880 DUF4376 domain-containing protein -
OF884_RS09615 2010776..2011108 + 333 WP_031609875.1 DUF1353 domain-containing protein -
OF884_RS09620 2011157..2011266 + 110 Protein_1882 tail fiber assembly protein -
OF884_RS09625 2011357..2011542 - 186 WP_012218702.1 PagK family vesicle-borne virulence factor -
OF884_RS09630 2011785..2011982 - 198 Protein_1884 tail fiber assembly protein -
OF884_RS09635 2011978..2012748 - 771 WP_001652627.1 transporter substrate-binding domain-containing protein -
OF884_RS09640 2012824..2012916 + 93 Protein_1886 DUF4113 domain-containing protein -
OF884_RS09645 2013239..2013367 + 129 Protein_1887 helix-turn-helix domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2002959..2036915 33956


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T260404 NZ_CP107010:2008661-2008764 [Salmonella enterica subsp. enterica serovar Paratyphi B]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT260404 NZ_CP107010:c2008766-2008621 [Salmonella enterica subsp. enterica serovar Paratyphi B]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References