Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/Txe-YefM
Location 1979599..1980101 Replicon chromosome
Accession NZ_CP107009
Organism Halomonas sp. LR3S48

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag OCT51_RS09265 Protein ID WP_263583589.1
Coordinates 1979838..1980101 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCT51_RS09260 Protein ID WP_114573958.1
Coordinates 1979599..1979841 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCT51_RS09245 (OCT51_09245) 1975139..1976554 + 1416 WP_263583587.1 FAD-binding oxidoreductase -
OCT51_RS09250 (OCT51_09250) 1977644..1978648 + 1005 WP_263583588.1 PHB depolymerase family esterase -
OCT51_RS09255 (OCT51_09255) 1978765..1979313 + 549 Protein_1819 IS3 family transposase -
OCT51_RS09260 (OCT51_09260) 1979599..1979841 + 243 WP_114573958.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCT51_RS09265 (OCT51_09265) 1979838..1980101 + 264 WP_263583589.1 Txe/YoeB family addiction module toxin Toxin
OCT51_RS09270 (OCT51_09270) 1980101..1980268 + 168 WP_263583590.1 hypothetical protein -
OCT51_RS09275 (OCT51_09275) 1980393..1980899 + 507 WP_263583591.1 DUF6151 family protein -
OCT51_RS09280 (OCT51_09280) 1980946..1981386 + 441 WP_263583592.1 DUF1801 domain-containing protein -
OCT51_RS09285 (OCT51_09285) 1981728..1982297 + 570 WP_263583593.1 RNA polymerase sigma factor SigZ -
OCT51_RS09290 (OCT51_09290) 1982507..1984708 + 2202 WP_263583594.1 catalase/peroxidase HPI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1961854..1993518 31664


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10043.81 Da        Isoelectric Point: 10.3693

>T260397 WP_263583589.1 NZ_CP107009:1979838-1980101 [Halomonas sp. LR3S48]
VTWKLVYTKQAQKDAKKLASSGLKPKALELLALIAEDPYRKPPPFEKLIGDLAGAYSRRINIQHRLVYQVLEGERVIKVL
RLWSHYD

Download         Length: 264 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9037.13 Da        Isoelectric Point: 4.0066

>AT260397 WP_114573958.1 NZ_CP107009:1979599-1979841 [Halomonas sp. LR3S48]
MTGITATEARSNLYRLIDETAESHQPIVILGKRNKAVLVSEEDWSAIQETLYLLSVPGMRESIREGMDAPVDECDEELDW

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References