Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 984791..985179 Replicon chromosome
Accession NZ_CP107007
Organism Halomonas sp. GD1P12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OCT39_RS04570 Protein ID WP_263586514.1
Coordinates 984791..985045 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OCT39_RS04575 Protein ID WP_263586515.1
Coordinates 985042..985179 (-) Length 46 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCT39_RS04540 (OCT39_04540) 980008..980898 + 891 WP_263586508.1 DUF4747 family protein -
OCT39_RS04545 (OCT39_04545) 980900..981529 + 630 WP_263586509.1 hypothetical protein -
OCT39_RS04550 (OCT39_04550) 981626..982111 + 486 WP_263586510.1 hypothetical protein -
OCT39_RS04555 (OCT39_04555) 982104..982916 + 813 WP_263586511.1 hypothetical protein -
OCT39_RS04560 (OCT39_04560) 983041..984060 + 1020 WP_263586512.1 hypothetical protein -
OCT39_RS04565 (OCT39_04565) 984167..984679 + 513 WP_263586513.1 hypothetical protein -
OCT39_RS04570 (OCT39_04570) 984791..985045 - 255 WP_263586514.1 Txe/YoeB family addiction module toxin Toxin
OCT39_RS04575 (OCT39_04575) 985042..985179 - 138 WP_263586515.1 hypothetical protein Antitoxin
OCT39_RS04580 (OCT39_04580) 985192..985293 - 102 WP_263586516.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
OCT39_RS04585 (OCT39_04585) 985425..986960 - 1536 WP_263586517.1 Na+/H+ antiporter NhaC family protein -
OCT39_RS04590 (OCT39_04590) 987402..988616 + 1215 WP_263586518.1 GGDEF domain-containing protein -
OCT39_RS04595 (OCT39_04595) 988654..989142 - 489 WP_263586519.1 TspO/MBR family protein -
OCT39_RS04600 (OCT39_04600) 989283..989504 + 222 WP_263586520.1 VF530 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10073.59 Da        Isoelectric Point: 9.6072

>T260393 WP_263586514.1 NZ_CP107007:c985045-984791 [Halomonas sp. GD1P12]
VKLVFAENAWEDYLYWQKTDKKIPGRINKLIKEIERQPFEGVGKPEPLKHGFAGYWSRRINDEHRIVYKVADDALLIAQL
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 46 a.a.        Molecular weight: 5181.92 Da        Isoelectric Point: 4.1605

>AT260393 WP_263586515.1 NZ_CP107007:c985179-985042 [Halomonas sp. GD1P12]
MLLLEDFEALKETAYLLRSPNNARRLMDAMDELEKGGGQEKELLE

Download         Length: 138 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References