Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | V | Classification (family/domain) | ghoTS/ghoT-GhoS |
Location | 4214989..4215486 | Replicon | chromosome |
Accession | NZ_CP107004 | ||
Organism | Escherichia coli strain SY22A3 |
Toxin (Protein)
Gene name | ghoT | Uniprot ID | L4JJG6 |
Locus tag | OFB07_RS20775 | Protein ID | WP_001173343.1 |
Coordinates | 4214989..4215162 (-) | Length | 58 a.a. |
Antitoxin (Protein)
Gene name | ghoS | Uniprot ID | L4JK92 |
Locus tag | OFB07_RS20780 | Protein ID | WP_000398619.1 |
Coordinates | 4215190..4215486 (-) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OFB07_RS20765 (4211659) | 4211659..4213116 | + | 1458 | WP_000856829.1 | dipeptide/tripeptide permease DtpC | - |
OFB07_RS20770 (4213353) | 4213353..4214870 | + | 1518 | WP_001295074.1 | lysine--tRNA ligase | - |
OFB07_RS20775 (4214989) | 4214989..4215162 | - | 174 | WP_001173343.1 | type V toxin-antitoxin system toxin GhoT | Toxin |
OFB07_RS20780 (4215190) | 4215190..4215486 | - | 297 | WP_000398619.1 | type V toxin-antitoxin system endoribonuclease antitoxin GhoS | Antitoxin |
OFB07_RS20785 (4215713) | 4215713..4215985 | - | 273 | WP_000405651.1 | GNAT family N-acetyltransferase | - |
OFB07_RS20790 (4215997) | 4215997..4216227 | - | 231 | WP_000371704.1 | 4Fe-4S mono-cluster protein YjdI | - |
OFB07_RS20795 (4216408) | 4216408..4218039 | + | 1632 | WP_001216477.1 | sensor histidine kinase | - |
OFB07_RS20800 (4218036) | 4218036..4218755 | + | 720 | WP_000611288.1 | two-component system response regulator DcuR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QI41 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QBH6 |