Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3353227..3353372 Replicon chromosome
Accession NC_016845
Organism Klebsiella pneumoniae subsp. pneumoniae HS11286

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3353234..3353336 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3353227..3353372 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPHS_33670 3348759..3350192 + 1434 YP_005227667.1 putative methyltransferase -
KPHS_33680 3350239..3350547 + 309 YP_005227668.1 YebV family protein -
KPHS_33690 3350645..3350836 + 192 YP_005227669.1 YebW family protein -
KPHS_33700 3350833..3351486 - 654 YP_005227670.1 protein phosphatase 1 -
KPHS_33710 3351643..3352611 + 969 YP_005227671.1 DUF535 domain-containing protein -
KPHS_33720 3352716..3352859 + 144 YP_005227672.1 Ecr family regulatory small membrane protein -
- 3353227..3353372 + 146 - - Antitoxin
- 3353234..3353336 - 103 - - Toxin
KPHS_33730 3353495..3353833 - 339 YP_005227673.1 YebY family protein -
KPHS_33740 3353850..3354719 - 870 YP_005227674.1 putative resistance protein -
KPHS_33750 3354723..3355097 - 375 YP_005227675.1 CopC domain-containing protein YobA -
KPHS_33760 3355210..3355440 + 231 YP_005227676.1 DNA polymerase III subunit theta -
KPHS_33770 3355519..3356178 + 660 YP_005227677.1 exodeoxyribonuclease X -
KPHS_33780 3356182..3356631 - 450 YP_005227678.1 protease 2 -
KPHS_33790 3356631..3358208 - 1578 YP_005227679.1 protease 2 -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T26021 NC_016845:c3353336-3353234 [Klebsiella pneumoniae subsp. pneumoniae HS11286]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT26021 NC_016845:3353227-3353372 [Klebsiella pneumoniae subsp. pneumoniae HS11286]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References