Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012273..2012418 Replicon chromosome
Accession NZ_CP106912
Organism Klebsiella pneumoniae strain BSIKPN-9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012309..2012411 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012273..2012418 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OE131_RS09870 (OE131_09870) 2007403..2009463 + 2061 WP_004151449.1 oligopeptidase B -
OE131_RS09875 (OE131_09875) 2009467..2010126 - 660 WP_002911407.1 exodeoxyribonuclease X -
OE131_RS09880 (OE131_09880) 2010205..2010435 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OE131_RS09885 (OE131_09885) 2010548..2010922 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OE131_RS09890 (OE131_09890) 2010926..2011795 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OE131_RS09895 (OE131_09895) 2011812..2012150 + 339 WP_002911404.1 YebY family protein -
- 2012273..2012418 - 146 - - Antitoxin
- 2012309..2012411 + 103 - - Toxin
OE131_RS09900 (OE131_09900) 2012786..2012929 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OE131_RS09905 (OE131_09905) 2013034..2014002 - 969 WP_004151446.1 VirK/YbjX family protein -
OE131_RS09910 (OE131_09910) 2014159..2014812 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OE131_RS09915 (OE131_09915) 2014809..2015000 - 192 WP_002911395.1 YebW family protein -
OE131_RS09920 (OE131_09920) 2015098..2015337 - 240 WP_002911393.1 YebV family protein -
OE131_RS09925 (OE131_09925) 2015453..2016886 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T260015 NZ_CP106912:2012309-2012411 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT260015 NZ_CP106912:c2012418-2012273 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References