26001

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3839922..3840441 Replicon chromosome
Accession NC_016830
Organism Pseudomonas fluorescens F113

Toxin (Protein)


Gene name relE Uniprot ID G8Q6M7
Locus tag PSF113_RS46880 Protein ID WP_014338683.1
Coordinates 3840160..3840441 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A176NDU7
Locus tag PSF113_RS46875 Protein ID WP_024616638.1
Coordinates 3839922..3840170 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSF113_RS46860 3836341..3837348 + 1008 WP_014338680.1 AAA family ATPase -
PSF113_RS46865 3837450..3838007 + 558 WP_014338681.1 VWA domain-containing protein -
PSF113_RS46870 3838209..3839855 + 1647 WP_014338682.1 phospholipase -
PSF113_RS46875 3839922..3840170 + 249 WP_024616638.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PSF113_RS46880 3840160..3840441 + 282 WP_014338683.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSF113_RS46885 3840551..3840892 + 342 WP_014338684.1 hypothetical protein -
PSF113_RS46890 3841293..3842141 + 849 WP_003200222.1 transporter substrate-binding domain-containing protein -
PSF113_RS46895 3842196..3842858 + 663 WP_014338685.1 amino acid ABC transporter permease -
PSF113_RS46900 3842868..3843530 + 663 WP_014338686.1 amino acid ABC transporter permease -
PSF113_RS46905 3843527..3844318 + 792 WP_014338687.1 amino acid ABC transporter ATP-binding protein -
PSF113_RS46910 3844345..3844734 + 390 WP_013692714.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10917.63 Da        Isoelectric Point: 10.2243

>T26001 WP_014338683.1 NC_016830:3840160-3840441 [Pseudomonas fluorescens F113]
MTYELEFSDRAWKEWQKLGATLKEQFKKKLEERLVNPHVQADRLHGLGNAYKIKLRNAGYRLVYRVVDDLLVVTVIAVGK
RERGQVYDEAAKR

Download         Length: 282 bp

>T26001 NC_016830:3840160-3840441 [Pseudomonas fluorescens F113]
ATGACCTATGAGTTGGAGTTTTCCGATAGGGCATGGAAGGAATGGCAAAAGCTGGGAGCAACACTCAAGGAGCAATTCAA
GAAAAAGCTTGAAGAGCGACTGGTAAATCCGCATGTCCAGGCAGACCGACTGCACGGATTGGGCAATGCCTATAAAATCA
AGTTGCGTAACGCCGGCTATCGATTGGTTTATCGGGTAGTAGATGATTTGCTGGTTGTCACGGTAATCGCAGTGGGTAAG
CGCGAGCGCGGCCAAGTGTATGACGAGGCTGCCAAGCGATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9037.44 Da        Isoelectric Point: 4.4000

>AT26001 WP_024616638.1 NC_016830:3839922-3840170 [Pseudomonas fluorescens F113]
MTHIVLSQVVASISELKKNPMGTVAAGGGLSVAILNRNEPAFYCVPAREYEAMMDRLEDMELVALCRERENDPTIKVSLD
DL

Download         Length: 249 bp

>AT26001 NC_016830:3839922-3840170 [Pseudomonas fluorescens F113]
ATGACACATATCGTGCTTTCTCAGGTTGTAGCCAGTATTTCCGAGCTTAAGAAAAATCCGATGGGCACTGTCGCTGCCGG
GGGAGGGTTATCTGTAGCGATCCTCAACCGCAACGAGCCGGCTTTTTATTGCGTCCCTGCTAGGGAGTATGAAGCCATGA
TGGATCGGCTTGAAGACATGGAGTTGGTCGCTCTCTGCCGCGAGCGTGAAAATGATCCAACGATCAAGGTTTCTCTTGAT
GACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB G8Q6M7

Antitoxin

Source ID Structure
AlphaFold DB A0A176NDU7

References